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heparan sulfate-glucosamine 3-sulfotransferase 2

Summary

Gene Symbol

HS3ST2

Aliases

3OST2

Organism

Homo sapiens (human)

External Links

NCBI Gene

9956

GGDB ID

gg015

HGNC

5195

mRNA

NM_006043

map

16p12

Protein

NP_006034

OMIM

604056

KEGG Gene ID

hsa:9956

PubChem

9956

Alliance of Genome Resources

HGNC:5195

Annotation

Keyword

Disulfide bond
Glycoprotein
Golgi apparatus
Reference proteome
Signal-anchor
Transferase
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9Y278	Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
glycosaminoglycan biosynthetic process	IDA	9988768
heparan sulfate proteoglycan biosynthetic process, enzymatic modification

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

heparan sulfate proteoglycan metabolic process [inference]

heparan sulfate proteoglycan biosynthetic process, enzymatic modification

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

primary metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

heparan sulfate proteoglycan metabolic process [inference]

heparan sulfate proteoglycan biosynthetic process, enzymatic modification

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

heparan sulfate proteoglycan metabolic process [inference]

heparan sulfate proteoglycan biosynthetic process, enzymatic modification

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

heparan sulfate proteoglycan metabolic process [inference]

heparan sulfate proteoglycan biosynthetic process, enzymatic modification

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

heparan sulfate proteoglycan metabolic process [inference]

heparan sulfate proteoglycan biosynthetic process, enzymatic modification

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
membrane		9988767
Golgi membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
[heparan sulfate]-glucosamine 3-sulfotransferase 2 activity	IEA
sulfotransferase activity		9988767
[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity	IBA IDA TAS	9988768

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring sulphur-containing groups [inference]

sulfotransferase activity

heparan sulfate sulfotransferase activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

GlycoGene Database (GGDB)

GGDB ID

gg015

Gene Symbol

HS3ST2

Orthologous Gene

Displaying **all 2** entries
Species	Protein	mRNA
Rattus norvegicus	NP_852035	NM_181370
Mus musculus	XP_112440	XM_112440

KEGG BRITE Database

Orthology

K07808

Name

[heparan sulfate]-glucosamine 3-sulfotransferase 2 [EC:2.8.2.29]

References

9988768

Rhea

3'-phosphoadenylyl sulfate

H⁺ + adenosine 3',5'-bisphosphate

Enzyme

PMID

Disease

Disease Ontology

Displaying entries **1 - 10** of 23 in total

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DO ID	Disease Name	Source
DOID:0050865	tongue squamous cell carcinoma	DisGeNET
DOID:1324	lung cancer	DisGeNET DisGeNET Alliance of Genome Resources
DOID:1325	bronchus cancer	DisGeNET
DOID:1380	endometrial cancer	DisGeNET DisGeNET
DOID:1612	breast cancer	DisGeNET
DOID:162	cancer	DisGeNET DisGeNET DisGeNET
DOID:1749	squamous cell carcinoma	DisGeNET
DOID:1793	pancreatic cancer	Alliance of Genome Resources
DOID:219	colon cancer	Alliance of Genome Resources
DOID:2394	ovarian cancer	DisGeNET

Ortholog

Displaying entries **21 - 30** of 72 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Cercocebus atys	105586248		CERAT31891
Macaca fascicularis	102143244		MACFA24505
Macaca mulatta	699722		MACMU25854
Macaca nemestrina	105485010		MACNE37675
Papio anubis	101001300		PAPAN15214
Gorilla gorilla gorilla	101138321		GORGO12158
Pan paniscus	100969271		PANPA14819
Pan troglodytes	467924		PANTR11947
Pongo abelii	100459958		PONAB09964
Vulpes vulpes	112908295		VULVU34054

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Supported by JST NBDC Grant Number JPMJND2204

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GlyCosmos Portal v4.0.0

Last updated: August 19, 2024