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solute carrier family 23 member 1

Summary

Gene Symbol

SLC23A1

Organism

Homo sapiens (human)

External Links

NCBI Gene

9963

PubChem

9963

Alliance of Genome Resources

HGNC:10974

Annotation

Keyword

Alternative splicing
Cell membrane
Glycoprotein
Phosphoprotein
Reference proteome
Sodium transport
Symport
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9UHI7	Na(+)/L-ascorbic acid transporter 1 Sodium-dependent vitamin C transporter 1 Yolk sac permease-like molecule 3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 10 in total

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GO Term	Evidence Code	PMID
sodium ion transport	IDA	18094143
sodium ion transmembrane transport	IEA
nucleobase transport	TAS	10395795
response to toxic substance	IDA	17575980
lung development	IEA

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process

heterocycle metabolic process [inference]

lactone metabolic process [inference]

L-ascorbic acid metabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process

vitamin metabolic process [inference]

water-soluble vitamin metabolic process [inference]

L-ascorbic acid metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process

organic cyclic compound metabolic process [inference]

lactone metabolic process [inference]

L-ascorbic acid metabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process

heterocycle metabolic process [inference]

lactone metabolic process [inference]

L-ascorbic acid metabolic process

transmembrane transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

L-ascorbic acid transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

vitamin transmembrane transport [inference]

L-ascorbic acid transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

L-ascorbic acid transmembrane transport

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

response to stimulus [inference]

response to chemical [inference]

response to toxic substance

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport

sodium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

vitamin transport [inference]

vitamin transmembrane transport [inference]

L-ascorbic acid transmembrane transport

dehydroascorbic acid transport

transmembrane transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

L-ascorbic acid transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

vitamin transmembrane transport [inference]

L-ascorbic acid transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

L-ascorbic acid transmembrane transport

organic substance transport [inference]

carbohydrate transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

L-ascorbic acid transmembrane transport

organic anion transport [inference]

urate transport

carboxylic acid transport [inference]

carboxylic acid transmembrane transport [inference]

L-ascorbic acid transmembrane transport

dehydroascorbic acid transport

organic acid transport [inference]

carboxylic acid transport [inference]

carboxylic acid transmembrane transport [inference]

L-ascorbic acid transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

L-ascorbic acid transmembrane transport

nucleobase transport

nitrogen compound transport [inference]

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
cytoplasm	ISS
basal plasma membrane	IEA
intracellular organelle	IDA	15993839
plasma membrane	IDA TAS	10631088 36749388
apical plasma membrane	IDA	15993839 18094143 18247577 18417304 19216494

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

plasma membrane

plasma membrane region [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
sodium ion transmembrane transporter activity	IDA	18094143
transporter activity	IBA
L-ascorbate:sodium symporter activity	IDA	10556483 10631088 11895172 15993839 18094143 36749388
urate transmembrane transporter activity	IDA	36749388
protein binding	IPI	17474147 23599041 25416956 29892012

GO Hierarchy

molecular function

transporter activity

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

organic acid:sodium symporter activity [inference]

L-ascorbate:sodium symporter activity

carboxylic acid transmembrane transporter activity [inference]

organic anion transmembrane transporter activity [inference]

dehydroascorbic acid transmembrane transporter activity

carboxylic acid transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

carbohydrate:monoatomic cation symporter activity [inference]

L-ascorbate:sodium symporter activity

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

L-ascorbate:sodium symporter activity

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

L-ascorbate:sodium symporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

carbohydrate:monoatomic cation symporter activity [inference]

L-ascorbate:sodium symporter activity

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

L-ascorbate:sodium symporter activity

carbohydrate transmembrane transporter activity [inference]

carbohydrate:monoatomic cation symporter activity [inference]

L-ascorbate:sodium symporter activity

sugar transmembrane transporter activity [inference]

monosaccharide transmembrane transporter activity [inference]

nucleobase transmembrane transporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

L-ascorbate:sodium symporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

carbohydrate:monoatomic cation symporter activity [inference]

L-ascorbate:sodium symporter activity

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

L-ascorbate:sodium symporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

carbohydrate:monoatomic cation symporter activity [inference]

L-ascorbate:sodium symporter activity

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

L-ascorbate:sodium symporter activity

vitamin transmembrane transporter activity [inference]

salt transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

L-ascorbate:sodium symporter activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying entries **51 - 60** of 80 in total

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Species	Gene ID	Orthologous MAtrix
Cavia porcellus	100731136	CAVPO04157
Octodon degus	101568774	OCTDE21658
Heterocephalus glaber	101719450	HETGA16703
Monodelphis domestica	100025539	MONDO05315
Pelodiscus sinensis	102462648	PELSI14372
Anolis carolinensis	100556489	ANOCA00999
Ursus maritimus	103663945	URSMA04816
Bos indicus x Bos taurus	113895297	BOBOX24988
Microcebus murinus	105862605	MICMU06656
Otolemur garnettii	100958317	OTOGA18480