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solute carrier family 23 member 1

Summary

Gene Symbol

SLC23A1

Organism

Homo sapiens (human)

External Links

NCBI Gene

9963

PubChem

9963

Alliance of Genome Resources

HGNC:10974

Annotation

Keyword

Alternative splicing
Cell membrane
Glycoprotein
Phosphoprotein
Reference proteome
Sodium transport
Symport
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9UHI7	Na(+)/L-ascorbic acid transporter 1 Sodium-dependent vitamin C transporter 1 Yolk sac permease-like molecule 3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
dehydroascorbic acid transport	IMP	18247577
urate transport	IEA
brain development	ISS
L-ascorbic acid transmembrane transport	IDA	10556483 10631088 11895172 18247577 18417304 19216494
L-ascorbic acid metabolic process	TAS

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process

heterocycle metabolic process [inference]

lactone metabolic process [inference]

L-ascorbic acid metabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process

vitamin metabolic process [inference]

water-soluble vitamin metabolic process [inference]

L-ascorbic acid metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process

organic cyclic compound metabolic process [inference]

lactone metabolic process [inference]

L-ascorbic acid metabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process

heterocycle metabolic process [inference]

lactone metabolic process [inference]

L-ascorbic acid metabolic process

transmembrane transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

L-ascorbic acid transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

vitamin transmembrane transport [inference]

L-ascorbic acid transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

L-ascorbic acid transmembrane transport

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

response to stimulus [inference]

response to chemical [inference]

response to toxic substance

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport

sodium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

vitamin transport [inference]

vitamin transmembrane transport [inference]

L-ascorbic acid transmembrane transport

dehydroascorbic acid transport

transmembrane transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

L-ascorbic acid transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

vitamin transmembrane transport [inference]

L-ascorbic acid transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

L-ascorbic acid transmembrane transport

organic substance transport [inference]

carbohydrate transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

L-ascorbic acid transmembrane transport

organic anion transport [inference]

urate transport

carboxylic acid transport [inference]

carboxylic acid transmembrane transport [inference]

L-ascorbic acid transmembrane transport

dehydroascorbic acid transport

organic acid transport [inference]

carboxylic acid transport [inference]

carboxylic acid transmembrane transport [inference]

L-ascorbic acid transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

L-ascorbic acid transmembrane transport

nucleobase transport

nitrogen compound transport [inference]

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
cytoplasm	ISS
basal plasma membrane	IEA
intracellular organelle	IDA	15993839
plasma membrane	IDA TAS	10631088 36749388
apical plasma membrane	IDA	15993839 18094143 18247577 18417304 19216494

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

plasma membrane

plasma membrane region [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **6 - 8** of 8 in total

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GO Term	Evidence Code	PMID
nucleobase transmembrane transporter activity	TAS	10395795
L-ascorbic acid transmembrane transporter activity	IDA TAS	10631088 11895172 18247577 18417304 19216494
dehydroascorbic acid transmembrane transporter activity	IMP	18247577

GO Hierarchy

molecular function

transporter activity

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

organic acid:sodium symporter activity [inference]

L-ascorbate:sodium symporter activity

carboxylic acid transmembrane transporter activity [inference]

organic anion transmembrane transporter activity [inference]

dehydroascorbic acid transmembrane transporter activity

carboxylic acid transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

carbohydrate:monoatomic cation symporter activity [inference]

L-ascorbate:sodium symporter activity

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

L-ascorbate:sodium symporter activity

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

L-ascorbate:sodium symporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

carbohydrate:monoatomic cation symporter activity [inference]

L-ascorbate:sodium symporter activity

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

L-ascorbate:sodium symporter activity

carbohydrate transmembrane transporter activity [inference]

carbohydrate:monoatomic cation symporter activity [inference]

L-ascorbate:sodium symporter activity

sugar transmembrane transporter activity [inference]

monosaccharide transmembrane transporter activity [inference]

nucleobase transmembrane transporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

L-ascorbate:sodium symporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

carbohydrate:monoatomic cation symporter activity [inference]

L-ascorbate:sodium symporter activity

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

L-ascorbate:sodium symporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

carbohydrate:monoatomic cation symporter activity [inference]

L-ascorbate:sodium symporter activity

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

L-ascorbate:sodium symporter activity

vitamin transmembrane transporter activity [inference]

salt transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

L-ascorbate:sodium symporter activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying entries **1 - 10** of 80 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	177296	WB:WBGene00021994
Caenorhabditis elegans	183708	WB:WBGene00008252
Caenorhabditis elegans	187811	WB:WBGene00020004
Caenorhabditis elegans	188241	WB:WBGene00011593
Caenorhabditis elegans	188243	WB:WBGene00011595
Drosophila melanogaster	41259	FB:FBgn0037807
Callorhinchus milii	103186960		CALMI35751
Latimeria chalumnae	102366655		LATCH18129
Danio rerio	559435	ZFIN:ZDB-GENE-080804-2	DANRE21099
Ictalurus punctatus	108279286		ICTPU11569