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MIRAGE
cell division cycle 42
Summary
- Gene Symbol
-
- CDC42
- Aliases
-
- CDC42Hs
- G25K
- GTP binding protein, 25kDa
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Cell projection
- Cytoskeleton
- Differentiation
- Direct protein sequencing
- Disease variant
- GTP-binding
- Glycoprotein
- Hydrolase
- Intellectual disability
- Methylation
- Neurogenesis
- Phosphoprotein
- Prenylation
- Reference proteome
- Proteins
| UniProt | Protein Name |
|---|---|
| P60953 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| sprouting angiogenesis | ||
| cardiac conduction system development | ||
| cardiac neural crest cell migration involved in outflow tract morphogenesis | ||
| endocytosis | ||
| phagocytosis, engulfment |
GO Hierarchy
biological process
cellular process [inference]
developmental process [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
signal transduction
regulation of cell communication [inference]
regulation of cellular component biogenesis [inference]
positive regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of cellular localization [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi membrane | ||
| storage vacuole | ||
| cytoplasm | ||
| endoplasmic reticulum membrane | ||
| centrosome |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- cell division control protein 42
- Functional Category
-
- T: Signal transduction mechanisms
- U: Intracellular trafficking, secretion, and vesicular transport
| Gene Ontology |
|---|
| GTP binding |
| nucleotide binding |
| protein kinase binding |
| small GTPase-mediated signal transduction |
| InterPro |
|---|
| P-loop containing nucleoside triphosphate hydrolase |
| Small GTP-binding protein domain |
| Small GTPase Rho |
| Small GTPase |
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3355 | fibrosarcoma |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000006 | Autosomal dominant inheritance |
| HP:0000023 | Inguinal hernia |
| HP:0000028 | Cryptorchidism |
| HP:0000047 | Hypospadias |
| HP:0000119 | Abnormality of the genitourinary system |
| HP:0000122 | Unilateral renal agenesis |
| HP:0000126 | Hydronephrosis |
| HP:0000154 | Wide mouth |
| HP:0000219 | Thin upper lip vermilion |
| HP:0000252 | Microcephaly |
| Disease ID | Disease Name |
|---|---|
| ORPHA:487796 |
|
| OMIM:616737 |
|
PubChem Disease
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 998 | Xenbase:XB-GENE-967585 | ||
| 12540 | MOUSE41223 | ||
| 64465 | RATNO32917 | ||
| 336839 | DANRE02487 | ||
| 403934 | CANLF07059 | ||
| 445704 | CIOIN12393 | ||
| 456609 | PANTR20193 | ||
| 532712 | BOVIN25238 | ||
| 707637 | MACMU21578 | ||
| 780428 | PIGXX29246 |
