RES
1r:r1
REP
REP1:7o(4+1)2d=-1--1
RES
2b:b-dglc-HEX-1:5|6:d
3b:b-dglc-HEX-1:5|6:d
4s:n-acetyl
5b:a-dgal-HEX-1:5|6:a
6s:n-acetyl
7b:a-dgal-HEX-1:5|6:a
8s:n-acetyl
9s:amino
10s:amino
11s:n-formyl
LIN
1:2o(2+1)3d
2:3d(2+1)4n
3:3o(3+1)5d
4:5d(2+1)6n
5:5o(4+1)7d
6:7d(2+1)8n
7:7d(6+1)9n
8:5d(6+1)10n
9:2d(4+1)11n

• Thirumalapura NR et al. Structural analysis of the O-antigen of Francisella tularensis subspecies tularensis strain OSU 10. J Med Microbiol. 2005 Jul;54:(Pt 7):693-695. doi: 10.1099/jmm.0.45931-0. PMID: 15947437.

• Prior JL et al. Characterization of the O antigen gene cluster and structural analysis of the O antigen of Francisella tularensis subsp. tularensis. J Med Microbiol. 2003 Oct;52:(Pt 10):845-851. doi: 10.1099/jmm.0.05184-0. PMID: 12972577.

• Shilova NV et al. Changes in the repertoire of natural antibodies caused by immunization with bacterial antigens. Biochemistry (Mosc). 2011 Jul;76:(7):862-6. doi: 10.1134/S0006297911070170. PMID: 21999548.

• Conlan JW et al. Mice intradermally-inoculated with the intact lipopolysaccharide, but not the lipid A or O-chain, from Francisella tularensis LVS rapidly acquire varying degrees of enhanced resistance against systemic or aerogenic challenge with virulent strains of the pathogen. Microb Pathog. 2003 Jan;34:(1):39-45. doi: 10.1016/s0882-4010(02)00194-8. PMID: 12620383.

• Apicella MA et al. Identification, characterization and immunogenicity of an O-antigen capsular polysaccharide of Francisella tularensis. PLoS One. 2010 Jul 6;5:(7):e11060. doi: 10.1371/journal.pone.0011060. PMID: 20625403.

• Knirel' IuA et al. [Structure of lipopolysaccharides from gram-negative bacteria. III. Structure of O-specific polysaccharides]. Biokhimiia. 1994 Dec;59:(12):1784-851. PMID: 7533007.

• Vinogradov E et al. Characterization of the lipopolysaccharide O-antigen of Francisella novicida (U112). Carbohydr Res. 2004 Feb 25;339:(3):649-54. doi: 10.1016/j.carres.2003.12.013. PMID: 15013402.