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G37184KW

Summary

GlyTouCan ID: G37184KW
IUPAC Condensed: Neu5Ac(a2-8)Neu5Ac(a2-3)[Gal(b1-3)GalNAc(b1-4)]Gal(b1-4)Glc(b1-
Motifs: GD1b
Subsumption Level: Fully-defined saccharide
Monoisotopic Mass: 1289.44

External Links

GlyGen

G37184KW

ChEBI

59222

PubChem Compound

45266846

PubChem Substance

252286914

CarbBank

1192 1193 3592 3681 5187 6906 8149 8275 9157 9326 9830 9907 10498 10871 11740 12841 14381 14417 14437 14451 14497 14852 14910 15898 16080 17693 17989 18555 18651 18907 18958 19032 19035 19531 19547 20305 20345 20653 20660 20717 20991 21800 22055 22209 22216 22662 22727 23671 23848 23863 23883 24823 24828 24965 24990 25263 25285 25358 25412 25532 25590 25814 25880 25912 25927 25937 25950 25961 25988 26018 26029 26278 26341 26589 26621 26669 26743 26927 27247 27256 27331 27390 27478 27644 27675 27858 28326 28338 28526 28567 28947 29007 29151 29965 29990 30111 30316 30922 31631 32039 32406 32561 32588 32689 32699 32727 32749 32898 33191 33237 33252 33343 33632 33685 33779 33795 33902 33946 34106 34663 34667 34758 34817 34864 34926 35163 35271 35296 35312 35324 35330 35341 35356 35370 35390 35399 35415 35430 35436 35439 35445 35448 35452 35470 35479 35492 35497 35514 35517 35526 35534 35539 35562 35570 35578 35583 35600 35606 35623 35641 35662 35698 35706 35932 36131 36151 36172 36393 36495 36578 36640 36840 36870 36874 36892 36900 36970 37031 37225 37251 37274 37318 37346 37480 37548 37620 37646 38105 38119 38382 38627 39366 39392 39426 39785 40559 40737 40812 41105 41241 41529 41889 42049 42667 43346 43493 43612 43622 44049 44076 44181 44185 44194 44199 44205 44816 44833 44882 44954 45138 45147 45161 45250 45264 45353 45476 45483 45725 45746 45772 45853 46038 46204 46253 46269 46531 46535 46701 46925 46991 47013 47334 47432 47574 47669 47701 48177 48199 48213 48411 48427 48517 48542 48576 48618 48931 49454 49459 49478 49483 49495 49535 50184 50193 50217 50266 50703 50799

3D Structures

GLYCAM: Neup5Aca2-8Neup5Aca2-3[DGalpb1-3DGalpNAcb1-4]DGalpb1-4DGlcpb1-OH

GlycoShape

G37184KW

Organisms

Displaying entries **1 - 5** of 37 in total

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Organisms	Evidence
Physeter catodon (sperm whale)	GlyTouCan(glycome-db)
Oryctolagus cuniculus (rabbit)	GlyTouCan(glycome-db)
Chionodraco myersi (Myers' icefish)	GlyTouCan(glycome-db)
Gallus gallus (chicken)	GlyTouCan(glycome-db)
Felis catus (domestic cat)	GlyTouCan(glycome-db)

Taxonomic Hierarchy

root

cellular organisms [inference]

Eukaryota (eucaryotes) [inference]

Opisthokonta [inference]

Metazoa (metazoans) [inference]

Eumetazoa [inference]

Bilateria [inference]

Deuterostomia [inference]

Chordata (chordates) [inference]

Craniata [inference]

Vertebrata (vertebrates) [inference]

Gnathostomata (jawed vertebrates) [inference]

Teleostomi [inference]

Euteleostomi (bony vertebrates) [inference]

Sarcopterygii [inference]

Dipnotetrapodomorpha [inference]

Tetrapoda (tetrapods) [inference]

Amniota (amniotes) [inference]

Mammalia (mammals) [inference]

Theria [inference]

Eutheria (placentals) [inference]

Boreoeutheria [inference]

Laurasiatheria [inference]

Artiodactyla (even-toed ungulates & whales) [inference]

Whippomorpha [inference]

Cetacea (whales) [inference]

Odontoceti (tooth whales) [inference]

Delphinidae (marine dolphins) [inference]

Globicephala (pilot whales) [inference]

Globicephala macrorhynchus (short-finned pilot whale)

Delphinus [inference]

Delphinus delphis (saddleback dolphin)

Tursiops [inference]

Tursiops truncatus (common bottlenose dolphin)

Orcinus [inference]

Orcinus orca (killer whale)

Stenella [inference]

Stenella coeruleoalba (striped dolphin)

Phocoenidae (porpoises) [inference]

Phocoenoides [inference]

Phocoenoides dalli (Dall's porpoise)

Physeteridae (sperm whales) [inference]

Physeter [inference]

Physeter catodon (sperm whale)

Mysticeti (baleen whales) [inference]

Balaenopteridae (rorquals) [inference]

Balaenoptera [inference]

Suina [inference]

Suidae (pigs) [inference]

Sus [inference]

Sus scrofa (pig)

Ruminantia [inference]

Pecora [inference]

Bovidae [inference]

Bovinae [inference]

Bos (cattle) [inference]

Bos taurus (domestic cattle)

Eulipotyphla (hedgehogs, shrews, moles and others) [inference]

Soricidae (shrews)

Crocidurinae [inference]

Suncus (musk shrews) [inference]

Suncus murinus (house shrew)

Carnivora (carnivores) [inference]

Caniformia [inference]

Canidae (dog, coyote, wolf, fox) [inference]

Canis [inference]

Canis lupus (gray wolf) [inference]

Canis lupus familiaris (dog)

Feliformia [inference]

Felidae (cat family) [inference]

Felinae [inference]

Felis [inference]

Felis catus (domestic cat)

Euarchontoglires [inference]

Glires (Rodents and rabbits) [inference]

Rodentia (rodent) [inference]

Myomorpha (mice and others) [inference]

Muroidea [inference]

Cricetidae [inference]

Cricetinae (hamsters)

Phodopus [inference]

Phodopus sungorus

Muridae [inference]

Murinae [inference]

Mus (mice) [inference]

Mus [inference]

Mus musculus (house mouse)

Rattus

Lagomorpha [inference]

Leporidae (rabbits and hares) [inference]

Oryctolagus [inference]

Oryctolagus cuniculus (rabbit)

Primates [inference]

Haplorrhini [inference]

Simiiformes [inference]

Catarrhini [inference]

Hominoidea (apes) [inference]

Hominidae (great apes) [inference]

Homininae [inference]

Homo [inference]

Homo sapiens (human)

Cercopithecoidea [inference]

Cercopithecidae (Old World monkeys) [inference]

Cercopithecinae [inference]

Papio (baboons) [inference]

Papio hamadryas (hamadryas baboon)

Sauropsida (sauropsids) [inference]

Sauria (diapsids) [inference]

Archelosauria [inference]

Archosauria [inference]

Dinosauria [inference]

Saurischia [inference]

Theropoda [inference]

Coelurosauria [inference]

Aves (birds) [inference]

Neognathae [inference]

Galloanserae [inference]

Galliformes (landfowls) [inference]

Phasianidae (turkeys) [inference]

Phasianinae [inference]

Gallus [inference]

Gallus gallus (chicken)

Amphibia (amphibians) [inference]

Batrachia [inference]

Anura (frogs and toads) [inference]

Pipoidea [inference]

Pipidae (tongueless frogs) [inference]

Xenopodinae [inference]

Xenopus

Xenopus [inference]

Xenopus laevis (African clawed frog)

Actinopterygii (ray-finned fishes) [inference]

Actinopteri [inference]

Neopterygii [inference]

Teleostei (teleost fishes) [inference]

Osteoglossocephalai [inference]

Clupeocephala [inference]

Otomorpha [inference]

Ostariophysi [inference]

Otophysi [inference]

Cypriniphysae [inference]

Cypriniformes (carps and others) [inference]

Cyprinoidei [inference]

Cyprinidae [inference]

Cyprininae [inference]

Carassius [inference]

Carassius auratus (goldfish)

Cyprinus [inference]

Cyprinus carpio (common carp)

Leuciscidae [inference]

Leuciscinae [inference]

Scardinius [inference]

Scardinius erythrophthalmus (rudd)

Euteleosteomorpha [inference]

Neoteleostei [inference]

Eurypterygia [inference]

Ctenosquamata [inference]

Acanthomorphata [inference]

Euacanthomorphacea [inference]

Percomorphaceae [inference]

Ovalentaria [inference]

Cichlomorphae [inference]

Cichliformes (cichlids and convict blennies) [inference]

Cichlidae (cichlids)

African cichlids [inference]

Pseudocrenilabrinae [inference]

Oreochromini [inference]

Oreochromis [inference]

Oreochromis mossambicus (Mozambique tilapia)

Eupercaria [inference]

Perciformes (perches and others) [inference]

Notothenioidei [inference]

Channichthyidae (crocodile icefishes) [inference]

Chionodraco [inference]

Chionodraco myersi (Myers' icefish)

Nototheniidae (Antarctic cods) [inference]

Trematomus [inference]

Trematomus lepidorhinus (slender scalyhead)

Paracanthopterygii [inference]

Zeiogadaria [inference]

Gadariae [inference]

Gadiformes (cods and others) [inference]

Gadoidei [inference]

Gadidae (cods) [inference]

Gadus [inference]

Gadus morhua (Atlantic cod)

Chondrichthyes (cartilaginous fishes) [inference]

Elasmobranchii (elasmobranchs) [inference]

Batoidea (rays) [inference]

Rajiformes (skates) [inference]

Rajidae (hardnose skates) [inference]

Leucoraja [inference]

Leucoraja erinacea (little skate)

Torpediniformes [inference]

Narcinidae (numbfishes) [inference]

Discopyge [inference]

Discopyge tschudii (apron ray)

Torpedinidae (electric rays) [inference]

Torpedo [inference]

Torpedo marmorata (marbled electric ray)

GlycoGene Database (GGDB)

Displaying **all 4** entries
Gene Symbol	Donor	Acceptor	Reducing terminal(Acceptor)	Reference
ST8SIA6	CMP-Neu5Ac	G37184KW	Cer	11980897 16120058
ST3GAL6	CMP-Neu5Ac	G37184KW	ceramide	10206952
ST8SIA3	CMP-Neu5Ac	G37184KW	Cer	7782326
B3GALT4	UDP-Gal	G37184KW	Cer	9312075

KEGG BRITE Database

KEGG ID

G00115

Enzyme

References

7553668

Reactions

Displaying **all 2** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05948	2.4.1.62	G02657AK	G37184KW
R05949	2.4.3.2	G37184KW	G40183QN

GlycoEpitope

Epitope ID: EP0059

Sequence Descriptors

GlycoCT

RES
1b:b-dglc-HEX-1:5
2b:b-dgal-HEX-1:5
3b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
4s:n-acetyl
5b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d
6s:n-acetyl
7b:b-dgal-HEX-1:5
8s:n-acetyl
9b:b-dgal-HEX-1:5
LIN
1:1o(4+1)2d
2:2o(3+2)3d
3:3d(5+1)4n
4:3o(8+2)5d
5:5d(5+1)6n
6:2o(4+1)7d
7:7d(2+1)8n
8:7o(3+1)9d

WURCS

WURCS=2.0/4,6,5/[a2122h-1b_1-5][a2112h-1b_1-5][Aad21122h-2a_2-6_5*NCC/3=O][a2112h-1b_1-5_2*NCC/3=O]/1-2-3-3-4-2/a4-b1_b3-c2_b4-e1_c8-d2_e3-f1

Literature

Displaying entries **1 - 10** of 28 in total

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PubMed ID	Title	First Author	Publication Date	Source
17855742	Sulfatide binding properties of murine and human antiganglioside antibodies	Townson K	2007 Aug 17	GlyGen GlycoEpitope
16564536	Comprehensive analysis of monoclonal antibodies against detergent-insoluble membrane/lipid rafts of HL60 cells	Yamazaki Y	2006 Apr 20	GlyGen GlycoEpitope
16120058	Molecular cloning and expression of a human hST8Sia VI (alpha2,8-sialyltransferase) responsible for the synthesis of the diSia motif on O-glycosylproteins	Teintenier-Lelièvre M	2005 Dec 06	PubChem
15967512	Characterisation of the immunoglobulin variable region gene usage encoding the murine anti-ganglioside antibody repertoire	Boffey J	2005 Aug	GlyGen GlycoEpitope
15464996	Gangliosides of organ-confined versus metastatic androgen-receptor-negative prostate cancer	Ravindranath MH	2004 Nov 05	GlyGen GlycoEpitope
15223242	Innate murine B cells produce anti-disialosyl antibodies reactive with Campylobacter jejuni LPS and gangliosides that are polyreactive and encoded by a restricted set of unmutated V genes	Boffey J	2004 Jul	GlyGen GlycoEpitope
14960498	Synthetic disialylgalactose immunoadsorbents deplete anti-GQ1b antibodies from autoimmune neuropathy sera	Willison HJ	2003 Nov 07	GlyGen GlycoEpitope
12851687	Expansion of natural killer cells in mice transgenic for IgM antibody to ganglioside GD2: demonstration of prolonged survival after challenge with syngeneic tumor cells	Kawashima I	2003 Aug	GlyGen GlycoEpitope
11878808	Immunoglobulin G-class mouse monoclonal antibodies to major brain gangliosides	Schnaar RL	2002 Mar 15	GlyGen GlycoEpitope
11980897	Molecular cloning and expression of a sixth type of alpha 2,8-sialyltransferase (ST8Sia VI) that sialylates O-glycans	Takashima S	2002 Jul 05	PubChem

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

KEGG BRITE Database

GlycoEpitope

Sequence Descriptors

International Collaboration

Acknowledgements