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serine hydroxymethyltransferase 2

Summary

Gene Symbol

SHMT2

Organism

Oryctolagus cuniculus (rabbit)

External Links

NCBI Gene: 100009293
KEGG Gene ID: ocu:100009293
PubChem: 100009293

Annotation

Keyword

Acetylation
Cytoplasm
Direct protein sequencing
Mitochondrion inner membrane
Mitochondrion nucleoid
Nucleus
One-carbon metabolism
Phosphoprotein
Pyridoxal phosphate
Reference proteome
Transferase
Transit peptide

Proteins

Displaying 1 entry
UniProt	Protein Name
P14519	Glycine hydroxymethyltransferase Serine methylase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

1

2

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Last »
GO Term	Evidence Code	PMID
tetrahydrofolate interconversion	IEA	22301074 30032202
protein homotetramerization	IEA	30032202
L-serine catabolic process	IEA	30032202
folic acid metabolic process	IEA	30032202
response to type I interferon	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

amide metabolic process [inference]

folic acid metabolic process

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

L-serine metabolic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

cellular modified amino acid metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

nucleobase metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

pteridine-containing compound metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

heterocycle biosynthetic process [inference]

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

aromatic compound biosynthetic process [inference]

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

organic cyclic compound biosynthetic process [inference]

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

L-serine metabolic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

dicarboxylic acid metabolic process [inference]

folic acid metabolic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

cellular modified amino acid metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

aromatic compound biosynthetic process [inference]

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

pteridine-containing compound metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

one-carbon metabolic process [inference]

tetrahydrofolate interconversion

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

heterocycle biosynthetic process [inference]

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

aromatic compound biosynthetic process [inference]

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

pteridine-containing compound metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

L-serine metabolic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

L-serine metabolic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

dicarboxylic acid metabolic process [inference]

folic acid metabolic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

one-carbon metabolic process [inference]

tetrahydrofolate interconversion

vitamin metabolic process [inference]

water-soluble vitamin metabolic process [inference]

folic acid metabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

L-serine metabolic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

dicarboxylic acid metabolic process [inference]

folic acid metabolic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

pteridine-containing compound metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

organic cyclic compound biosynthetic process [inference]

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

L-serine metabolic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

cellular modified amino acid metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

nucleobase metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

pteridine-containing compound metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

organic cyclic compound biosynthetic process [inference]

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid metabolic process [inference]

serine family amino acid metabolic process [inference]

glycine metabolic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

L-serine metabolic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

dicarboxylic acid metabolic process [inference]

folic acid metabolic process

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

cellular modified amino acid metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

aromatic compound biosynthetic process [inference]

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

pteridine-containing compound metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

one-carbon metabolic process [inference]

tetrahydrofolate interconversion

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

alpha-amino acid catabolic process [inference]

serine family amino acid catabolic process [inference]

L-serine catabolic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process [inference]

alpha-amino acid biosynthetic process [inference]

serine family amino acid biosynthetic process [inference]

glycine biosynthetic process [inference]

glycine biosynthetic process from serine

heterocycle biosynthetic process [inference]

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

aromatic compound biosynthetic process [inference]

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

heterocycle biosynthetic process [inference]

nucleobase biosynthetic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

pteridine-containing compound metabolic process [inference]

folic acid-containing compound metabolic process [inference]

tetrahydrofolate metabolic process [inference]

tetrahydrofolate interconversion

folic acid metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process [inference]

purine nucleobase biosynthetic process

purine-containing compound biosynthetic process [inference]

purine nucleobase biosynthetic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization [inference]

protein homotetramerization

protein tetramerization [inference]

protein homotetramerization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization [inference]

protein homotetramerization

protein tetramerization [inference]

protein homotetramerization

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

response to type I interferon

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of cellular metabolic process [inference]

regulation of generation of precursor metabolites and energy [inference]

regulation of cellular respiration [inference]

regulation of aerobic respiration [inference]

regulation of oxidative phosphorylation

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of generation of precursor metabolites and energy [inference]

regulation of cellular respiration [inference]

regulation of aerobic respiration [inference]

regulation of oxidative phosphorylation

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GO Term	Evidence Code	PMID
nucleus	IEA	30032202
mitochondrial inner membrane	IEA	30032202
cytosol	IEA	30032202
cytoplasm	IEA	30032202
BRISC complex	IEA	30032202

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

BRISC complex

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

mitochondrial matrix

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

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GO Term	Evidence Code	PMID
zinc ion binding	IEA	30032202
glycine hydroxymethyltransferase activity	IEA	22301074 30032202
protein homodimerization activity	IEA	30032202
mRNA 5'-UTR binding	IEA	30032202
pyridoxal phosphate binding	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring one-carbon groups [inference]

hydroxymethyl-, formyl- and related transferase activity [inference]

glycine hydroxymethyltransferase activity

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

small molecule binding [inference]

vitamin binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

organic acid binding [inference]

carboxylic acid binding [inference]

amino acid binding [inference]

serine binding

heterocyclic compound binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

ion binding [inference]

anion binding [inference]

pyridoxal phosphate binding

carboxylic acid binding [inference]

amino acid binding [inference]

serine binding

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

serine binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding [inference]

mRNA binding [inference]

mRNA 5'-UTR binding

translation regulator activity, nucleic acid binding [inference]

mRNA regulatory element binding translation repressor activity

vitamin B6 binding [inference]

pyridoxal phosphate binding

translation regulator activity [inference]

translation repressor activity [inference]

mRNA regulatory element binding translation repressor activity

translation regulator activity, nucleic acid binding [inference]

mRNA regulatory element binding translation repressor activity

Gene Ontology information from NCBI Gene and UniProt.

Rhea

RHEA:15481

H₂O + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine

L-serine + (6S)-5,6,7,8-tetrahydrofolate

Enzyme

2.1.2.1

PMID

Ortholog

Displaying entries **1 - 10** of 74 in total

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Species	Gene ID	Orthologous MAtrix
Ciona intestinalis	100176513	CIOIN01417
Callorhinchus milii	103189062	CALMI40581
Latimeria chalumnae	102355076	LATCH20215
Danio rerio	100144628	DANRE39366
Astyanax mexicanus	103047201	ASTMX01040
Electrophorus electricus	113578000	ELEEL20725
Salmo trutta	115207343	SALTR35670
Gadus morhua	115557090	GADMO10863
Oryzias latipes	101164393	ORYLA13940
Oreochromis niloticus	100690586	ORENI56848

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

International Collaboration

Acknowledgements