GlyCosmos Portal

Submissions

glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)

Summary

Gene Symbol

GAD2

Organism

Malus domestica (apple)

External Links

NCBI Gene: 103444237
KEGG Gene ID: mdm:103444237
PubChem: 103444237

Annotation

Keyword

Decarboxylase
Pyridoxal phosphate
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
V9SJB6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
glutamate catabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

glutamate metabolic process [inference]

glutamate catabolic process

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process [inference]

glutamate catabolic process

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process [inference]

glutamate catabolic process

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid metabolic process [inference]

glutamate metabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

primary metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process [inference]

glutamate catabolic process

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process [inference]

glutamate catabolic process

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid metabolic process [inference]

glutamate metabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process [inference]

glutamate catabolic process

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid metabolic process [inference]

glutamate metabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process [inference]

glutamate catabolic process

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

glutamate metabolic process [inference]

glutamate catabolic process

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid metabolic process [inference]

glutamate metabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

dicarboxylic acid catabolic process [inference]

glutamate catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

glutamate catabolic process

Displaying 1 entry
GO Term	Evidence Code	PMID
cytosol	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

Displaying **all 2** entries
GO Term	Evidence Code	PMID
glutamate decarboxylase activity	IEA	22301074 30032202
pyridoxal phosphate binding	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

lyase activity [inference]

carbon-carbon lyase activity [inference]

carboxy-lyase activity [inference]

glutamate decarboxylase activity

binding [inference]

small molecule binding [inference]

vitamin binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

heterocyclic compound binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

ion binding [inference]

anion binding [inference]

pyridoxal phosphate binding

organic cyclic compound binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K01580

Name

glutamate decarboxylase [EC:4.1.1.15]

References

Rhea

RHEA:17785

H⁺ + L-glutamate

CO₂ + 4-aminobutanoate

Enzyme

4.1.1.15

PMID

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements