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polypeptide N-acetylgalactosaminyltransferase 3

Summary

Gene Symbol

Galnt3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

14425

KEGG Gene ID

mmu:14425

PubChem

14425

Alliance of Genome Resources

MGI:894695

Annotation

Keyword

Disulfide bond
Glycoprotein
Glycosyltransferase
Golgi apparatus
Lectin
Manganese
Metal-binding
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P70419	Polypeptide GalNAc transferase 3 Protein-UDP acetylgalactosaminyltransferase 3 UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein O-linked glycosylation via threonine	IEA ISO
protein O-linked glycosylation	IBA IDA IMP ISO	19213845 8912633
spermatogenesis	IMP	19213845
protein O-linked glycosylation via serine	IEA ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

protein O-linked glycosylation via serine

peptidyl-threonine modification [inference]

protein O-linked glycosylation via threonine

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

protein O-linked glycosylation via serine

peptidyl-threonine modification [inference]

protein O-linked glycosylation via threonine

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

protein O-linked glycosylation via serine

peptidyl-threonine modification [inference]

protein O-linked glycosylation via threonine

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

protein O-linked glycosylation via serine

peptidyl-threonine modification [inference]

protein O-linked glycosylation via threonine

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

protein O-linked glycosylation via serine

peptidyl-threonine modification [inference]

protein O-linked glycosylation via threonine

reproductive process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

multicellular organismal reproductive process [inference]

gamete generation [inference]

male gamete generation [inference]

spermatogenesis

developmental process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

Displaying **all 3** entries
GO Term	Evidence Code	PMID
Golgi apparatus	IBA ISO
Golgi cisterna membrane	IEA
perinuclear region of cytoplasm	IEA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

Golgi cisterna membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

perinuclear region of cytoplasm

Displaying **all 4** entries
GO Term	Evidence Code	PMID
manganese ion binding	IEA ISO
polypeptide N-acetylgalactosaminyltransferase activity	IBA IDA ISO	8912633
calcium ion binding	IEA ISO
carbohydrate binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylgalactosaminyltransferase activity [inference]

polypeptide N-acetylgalactosaminyltransferase activity

hexosyltransferase activity [inference]

acetylgalactosaminyltransferase activity [inference]

polypeptide N-acetylgalactosaminyltransferase activity

catalytic activity, acting on a protein [inference]

polypeptide N-acetylgalactosaminyltransferase activity

binding [inference]

carbohydrate binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

transition metal ion binding [inference]

manganese ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

polypeptide N-acetylgalactosaminyltransferase 3

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
P: Inorganic ion transport and metabolism

Displaying **all 3** entries
Gene Ontology
polypeptide N-acetylgalactosaminyltransferase activity
protein O-linked glycosylation
transferase activity

Displaying **all 5** entries
InterPro
Glycosyltransferase 2-like
N-acetylgalactosaminyltransferase
Nucleotide-diphospho-sugar transferases
Ricin B, lectin domain
Ricin B-like lectins

KEGG BRITE Database

Orthology

K00710

Name

polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41]

References

9295285

Rhea

RHEA:23956

UDP-N-acetyl-α-D-galactosamine

H⁺ + UDP

Enzyme

2.4.1.41

PMID

RHEA:52424

UDP-N-acetyl-α-D-galactosamine

H⁺ + UDP

Enzyme

2.4.1.41

PMID

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0111063	hyperphosphatemic familial tumoral calcinosis	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **140** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	2591		HGNC:4125	HUMAN65332
Drosophila melanogaster	35627		FB:FBgn0027558
Drosophila melanogaster	36717		FB:FBgn0034025
Rattus norvegicus	366061	10116_1:00128d	RGD:1306443	RATNO28570
Pan troglodytes	459702			PANTR29015
Canis lupus familiaris	478774			CANLF13925
Bos taurus	535458			BOVIN24154
Macaca mulatta	707605			MACMU06558
Monodelphis domestica	100023186			MONDO22354
Equus caballus	100051940			HORSE13851

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements