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Chondroitin sulfate synthase sqv-5;Hexosyltransferase

Summary

Gene Symbol

sqv-5

Organism

Caenorhabditis elegans

External Links

NCBI Gene

172851

KEGG Gene ID

cel:CELE_T24D1.1

PubChem

172851

Alliance of Genome Resources

WB:WBGene00005023

Annotation

Keyword

Alternative splicing
Coiled coil
Glycoprotein
Golgi apparatus
Metal-binding
Proteomics identification
Reference proteome
Signal-anchor
Transferase
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q7Z1Z1	Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase 1 Glucuronylgalactosylproteoglycan 4-beta-N- acetylgalactosaminyltransferase N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1 Squashed vulva protein 5
A0A0K3ATP9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
positive regulation of vulval development	IMP	27482894
chondroitin sulfate biosynthetic process	IBA
reproduction
egg-laying behavior	IMP	9927677
vulval development	IMP	9927677

GO Hierarchy

biological process

reproduction

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

chondroitin sulfate biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process [inference]

chondroitin sulfate biosynthetic process

mucopolysaccharide metabolic process [inference]

chondroitin sulfate metabolic process [inference]

chondroitin sulfate biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

chondroitin sulfate biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

chondroitin sulfate biosynthetic process

sulfur compound biosynthetic process [inference]

chondroitin sulfate biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

chondroitin sulfate biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

chondroitin sulfate biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

chondroitin sulfate biosynthetic process

cellular metabolic process [inference]

sulfur compound metabolic process [inference]

chondroitin sulfate metabolic process [inference]

chondroitin sulfate biosynthetic process

sulfur compound biosynthetic process [inference]

chondroitin sulfate biosynthetic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

chondroitin sulfate biosynthetic process

sulfur compound biosynthetic process [inference]

chondroitin sulfate biosynthetic process

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

chondroitin sulfate biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process [inference]

chondroitin sulfate biosynthetic process

mucopolysaccharide metabolic process [inference]

chondroitin sulfate metabolic process [inference]

chondroitin sulfate biosynthetic process

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

chondroitin sulfate biosynthetic process

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

chondroitin sulfate biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process [inference]

chondroitin sulfate biosynthetic process

mucopolysaccharide metabolic process [inference]

chondroitin sulfate metabolic process [inference]

chondroitin sulfate biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

chondroitin sulfate biosynthetic process

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

chondroitin sulfate biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process [inference]

chondroitin sulfate biosynthetic process

mucopolysaccharide metabolic process [inference]

chondroitin sulfate metabolic process [inference]

chondroitin sulfate biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

chondroitin sulfate biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

chondroitin sulfate biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

chondroitin sulfate biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

chondroitin sulfate biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

sulfur compound metabolic process [inference]

chondroitin sulfate metabolic process [inference]

chondroitin sulfate biosynthetic process

sulfur compound biosynthetic process [inference]

chondroitin sulfate biosynthetic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process [inference]

chondroitin sulfate biosynthetic process

sulfur compound biosynthetic process [inference]

chondroitin sulfate biosynthetic process

reproductive process

reproductive behavior [inference]

egg-laying behavior

multicellular organismal process [inference]

behavior [inference]

reproductive behavior [inference]

egg-laying behavior

developmental process [inference]

anatomical structure morphogenesis [inference]

tissue morphogenesis [inference]

morphogenesis of an epithelium

anatomical structure development [inference]

animal organ development [inference]

vulval development

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of developmental process [inference]

positive regulation of vulval development

regulation of developmental process [inference]

regulation of vulval development [inference]

positive regulation of vulval development

positive regulation of developmental process [inference]

positive regulation of vulval development

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cytoplasm	IDA	12761549
membrane	IEA
Golgi apparatus	IEA
Golgi cisterna membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

membrane

organelle membrane [inference]

Golgi cisterna membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
acetylgalactosaminyltransferase activity	IEA
transferase activity	IEA
enzyme binding	IPI	17237233
glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	IBA IEA
N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylgalactosaminyltransferase activity

glucuronosyltransferase activity [inference]

N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity

hexosyltransferase activity [inference]

acetylgalactosaminyltransferase activity

glucuronosyltransferase activity [inference]

N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity

binding [inference]

protein binding [inference]

enzyme binding

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K13499

Name

chondroitin sulfate synthase [EC:2.4.1.175 2.4.1.226]

References

Reactions

Displaying **all 4** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05931	2.4.1.226	G40609EP	G09318DC
R05934	2.4.1.175	G91368UC	G66923HV
R05932	2.4.1.175	G09318DC	G95036CM
R05933	2.4.1.226	G95036CM	G91368UC

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
cytoplasm	PMID:12761549 PMID:15485872

Rhea

RHEA:55000

UDP-N-acetyl-α-D-galactosamine

H⁺ + UDP

Enzyme

2.4.1.175

PMID

RHEA:54996

UDP-α-D-glucuronate

H⁺ + UDP

Enzyme

2.4.1.226

PMID

RHEA:23428

UDP-α-D-glucuronate

H⁺ + UDP

Enzyme

2.4.1.226

PMID

RHEA:20800

UDP-N-acetyl-α-D-galactosamine

H⁺ + UDP

Enzyme

2.4.1.175

PMID

RHEA:23464

UDP-N-acetyl-α-D-galactosamine

H⁺ + UDP

Enzyme

2.4.1.174

PMID

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0050814	temtamy preaxial brachydactyly syndrome	Alliance of Genome Resources

Ortholog

Displaying **all 10** entries
Species	Gene ID	Alliance of Genome Resources
Drosophila melanogaster	32497	FB:FBgn0030662
Danio rerio	324407	ZFIN:ZDB-GENE-030131-3127
Danio rerio	368477	ZFIN:ZDB-GENE-030616-4
Xenopus tropicalis	100036707	Xenbase:XB-GENE-961883
Homo sapiens	22856	HGNC:17198
Homo sapiens	337876	HGNC:24293
Mus musculus	78923	MGI:1926173
Mus musculus	269941	MGI:2681120
Rattus norvegicus	291577	RGD:1560819
Rattus norvegicus	292999	RGD:1311904