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carbohydrate sulfotransferase 8

Summary

Gene Symbol

CHST8

Aliases

GALNAC4ST-1

Organism

Homo sapiens (human)

External Links

NCBI Gene

64377

GGDB ID

gg045

HGNC

15993

mRNA

NM_022467

map

19q13.1

Protein

NP_071912

OMIM

610190

KEGG Gene ID

hsa:64377

PubChem

64377

Alliance of Genome Resources

HGNC:15993

Annotation

Keyword

Carbohydrate metabolism
Glycoprotein
Golgi apparatus
Reference proteome
Signal-anchor
Transferase
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9H2A9	GalNAc-4-O-sulfotransferase 1 N-acetylgalactosamine-4-O-sulfotransferase 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
sulfur compound metabolic process	IDA	11445554
hormone biosynthetic process	IEP	10988300
proteoglycan biosynthetic process	IBA IDA	10988300
central nervous system development	NAS	10988300
carbohydrate biosynthetic process	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

biosynthetic process [inference]

hormone biosynthetic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

carbohydrate biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

hormone metabolic process [inference]

hormone biosynthetic process

cellular metabolic process [inference]

sulfur compound metabolic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

carbohydrate biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

carbohydrate biosynthetic process

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

carbohydrate biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

organonitrogen compound biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

sulfur compound metabolic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

glycoprotein biosynthetic process [inference]

proteoglycan biosynthetic process

developmental process [inference]

anatomical structure development [inference]

system development [inference]

central nervous system development

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

hormone biosynthetic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
membrane	NAS	10988300
Golgi membrane	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
N-acetylgalactosamine 4-O-sulfotransferase activity	IDA TAS	10988300 11001942 11445554
sulfotransferase activity	IBA
protein binding	IPI	32814053

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring sulphur-containing groups [inference]

sulfotransferase activity

N-acetylgalactosamine 4-O-sulfotransferase activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000124302

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

GlycoGene Database (GGDB)

GGDB ID

gg045

Gene Symbol

CHST8

Reactions

Displaying **all 2** entries
Donor	Acceptor	Product	Reference
PAPS	G00057MO		11139592
PAPS	G71793UG		10988300 12080076

Orthologous Gene

Displaying **all 2** entries
Species	Protein	mRNA
Rattus norvegicus	XP_218506	XM_218506
Mus musculus	NP_780349	NM_175140

KEGG BRITE Database

Orthology

K09672

Name

carbohydrate 4-sulfotransferase 8 [EC:2.8.2.-]

References

Disease

Disease Ontology

Displaying entries **1 - 10** of 14 in total

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DO ID	Disease Name	Source
DOID:0060283	peeling skin syndrome	DisGeNET
DOID:0080199	colorectal carcinoma	DisGeNET
DOID:2841	asthma	DisGeNET
DOID:3310	atopic dermatitis	DisGeNET
DOID:37	skin disease	DisGeNET
DOID:418	systemic scleroderma	DisGeNET
DOID:419	scleroderma	DisGeNET
DOID:4398	pustulosis of palm and sole	DisGeNET
DOID:5672	large intestine cancer	DisGeNET
DOID:8893	psoriasis	DisGeNET

PubChem Disease

KEGG Diseases

Peeling skin syndrome

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

Ortholog

Displaying entries **1 - 10** of 61 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	38249	FB:FBgn0035287
Drosophila melanogaster	326156	FB:FBgn0032618
Latimeria chalumnae	102362520		LATCH08498
Danio rerio	795008	ZFIN:ZDB-GENE-090313-104
Danio rerio	796549	ZFIN:ZDB-GENE-090410-1
Astyanax mexicanus	103031733		ASTMX08304
Ictalurus punctatus	108269398		ICTPU34249
Xenopus laevis	108704091	Xenbase:XB-GENE-17339445
Xenopus laevis	108714112	Xenbase:XB-GENE-6487999
Xenopus tropicalis	779984	Xenbase:XB-GENE-987442

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

GlycoGene Database (GGDB)

KEGG BRITE Database

PubChem Disease

International Collaboration

Acknowledgements