ST3 beta-galactoside alpha-2,3-sialyltransferase 2

Summary
Gene Symbol
  • ST3GAL2
Aliases
  • ST3GALII
  • ST3GalA.2
Organism
Homo sapiens (human)
External Links
NCBI Gene
6483
GGDB ID
HGNC
10863
mRNA
map
  • 16q22.1
Protein
OMIM
KEGG Gene ID
hsa:6483
PubChem
6483
Alliance of Genome Resources
Annotation
Keyword
  • Disulfide bond
  • Glycoprotein
  • Glycosyltransferase
  • Golgi apparatus
  • Lipid metabolism
  • Reference proteome
  • Secreted
  • Signal-anchor
  • Transmembrane helix
Proteins
Displaying all 2 entries
UniProt Protein Name
B3KXG9
  • Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase
  • Monosialoganglioside sialyltransferase
Q16842
  • Gal-NAc6S
  • Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase
  • Monosialoganglioside sialyltransferase
  • ST3Gal II
  • ST3GalA.2
  • Sialyltransferase 4B
Gene Ontology (GO)
GO Hierarchy
Human Protein Atlas
ENSG00000157350

soft tissue soft tissue blood blood blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node kidney kidney adrenal gland adrenal gland breast breast duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland nasopharynx nasopharynx tongue tonsil tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder ductus deferens ductus deferens seminal vesicle seminal vesicle seminal vesicle seminal vesicle testis testis epididymis epididymis brain smooth muscle urinary bladder prostate bone marrow skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus cartilage sole of foot sole of foot soft tissue blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lactating breast lactating breast kidney kidney adrenal gland adrenal gland duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland salivary gland salivary gland salivary gland salivary gland salivary gland nasopharynx tongue tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder brain skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus smooth muscle urinary bladder vagina ovary ovary fallopian tube fallopian tube endometrium placenta cervix cervix bone marrow cartilage sole of foot sole of foot olfactory region cerebral cortex cerebellum medulla pons midbrain pituitary gland hypothalamus amygdala thalamus choroid plexus choroid plexus corpus callosum basal ganglia substantia nigra dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe caudate hippocampus retina retina

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

GlycoGene Database (GGDB)
GGDB ID
gg049
Gene Symbol
  • ST3GAL2
Reactions
Displaying 1 entry
Donor Acceptor Product Reference
CMP-Neu5Ac
G00031MO
G65562ZE
Displaying all 3 entries
Donor Acceptor Product Reference
CMP-Neu5Ac
G48558GR
G46677TE
CMP-Neu5Ac
G00031MO
G65562ZE
CMP-Neu5Ac
G21856LC
G03277YI
Orthologous Gene
Displaying all 2 entries
Species Protein mRNA
Rattus norvegicus NP_113883 NM_031695
Mus musculus NP_033205 NM_009179
KEGG BRITE Database
Orthology
K03368
Name
beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4B) [EC:2.4.3.2 2.4.3.4]
References
Reactions
Disease
Disease Ontology
Displaying entries 1 - 10 of 12 in total
DO ID Disease Name Source
DOID:0050387 nonpapillary renal cell carcinoma
DOID:0060892 late onset Parkinson's disease
DOID:0111391 mucopolysaccharidosis IVA
DOID:12804 mucopolysaccharidosis IV
DOID:14330 Parkinson's disease
DOID:4450 renal cell carcinoma
DOID:4451 renal carcinoma
DOID:4464 collecting duct carcinoma
DOID:4465 papillary renal cell carcinoma
DOID:4467 clear cell renal cell carcinoma
LIPID MAPS Gene / Proteome Database
LMPD ID
LMP002419
Gene Name
ST3 beta-galactoside alpha-2,3-sialyltransferase 2

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024