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T4SS effector NAD-dependent ubiquitin ligase SdeA

Summary

Gene Symbol

sdeA

Organism

Legionella pneumophila

External Links

NCBI Gene: 66491287
PubChem: 66491287

Annotation

Keyword

3D-structure
Coiled coil
Glycosyltransferase
Isopeptide bond
Multifunctional enzyme
NAD
Nucleotide-binding
Nucleotidyltransferase
Reference proteome
Secreted
Thiol protease
Ubl conjugation
Ubl conjugation pathway
Virulence

Proteins

Displaying 1 entry
UniProt	Protein Name
Q5ZTK4	Effector protein SdeA

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein ubiquitination
protein deneddylation
proteolysis
protein deubiquitination

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein modification by small protein removal [inference]

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein modification by small protein removal [inference]

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein modification by small protein removal [inference]

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein modification by small protein removal [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein modification by small protein removal [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular region
host cell

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

host cellular component [inference]

host cell

Displaying entries **1 - 5** of 6 in total

1

2

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Last »
GO Term	Evidence Code	PMID
K63-linked deubiquitinase activity
NAD+-protein-arginine ADP-ribosyltransferase activity
deNEDDylase activity
cysteine-type peptidase activity
nucleotidyltransferase activity

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

pentosyltransferase activity [inference]

NAD+-protein ADP-ribosyltransferase activity [inference]

NAD+-protein-arginine ADP-ribosyltransferase activity

transferase activity, transferring phosphorus-containing groups [inference]

nucleotidyltransferase activity

hydrolase activity [inference]

peptidase activity [inference]

cysteine-type peptidase activity

ubiquitin-like protein peptidase activity [inference]

deNEDDylase activity

deubiquitinase activity [inference]

K63-linked deubiquitinase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

cysteine-type peptidase activity

ubiquitin-like protein peptidase activity [inference]

deNEDDylase activity

deubiquitinase activity [inference]

K63-linked deubiquitinase activity

NAD+-protein ADP-ribosyltransferase activity [inference]

NAD+-protein-arginine ADP-ribosyltransferase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding

Gene Ontology information from NCBI Gene and UniProt.

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024