GlyCosmos Portal

Submissions

bifunctional 2-dehydro-3-deoxygluconokinase/2-dehydro-3-deoxygalactonokinase

Summary

Gene Symbol

kdgK1

Organism

Haloferax volcanii DS2

External Links

NCBI Gene: 8924883
PubChem: 8924883

Annotation

Keyword

ATP-binding
Carbohydrate metabolism
Kinase
Reference proteome

Proteins

Displaying **all 3** entries
UniProt	Protein Name
D4GSE6	2-keto-3-deoxygluconate/2-keto-3-deoxygalactonate kinase KDG kinase KDGK-1
A0A384L344
A0A8T5D6J1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
D-glucuronate catabolic process
cellular response to DNA damage stimulus
D-galacturonate catabolic process
DNA damage response

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

monosaccharide catabolic process [inference]

D-galacturonate catabolic process

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

D-galacturonate catabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

D-glucuronate metabolic process [inference]

D-glucuronate catabolic process

galacturonate metabolic process [inference]

D-galacturonate metabolic process [inference]

D-galacturonate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

monosaccharide catabolic process [inference]

D-galacturonate catabolic process

D-galacturonate metabolic process [inference]

D-galacturonate catabolic process

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

D-galacturonate catabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

monosaccharide catabolic process [inference]

D-galacturonate catabolic process

D-galacturonate metabolic process [inference]

D-galacturonate catabolic process

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

D-glucuronate metabolic process [inference]

D-glucuronate catabolic process

galacturonate metabolic process [inference]

D-galacturonate metabolic process [inference]

D-galacturonate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

monosaccharide catabolic process [inference]

D-galacturonate catabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

monosaccharide catabolic process [inference]

D-galacturonate catabolic process

D-galacturonate metabolic process [inference]

D-galacturonate catabolic process

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

D-galacturonate catabolic process

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

D-glucuronate metabolic process [inference]

D-glucuronate catabolic process

galacturonate metabolic process [inference]

D-galacturonate metabolic process [inference]

D-galacturonate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

D-galacturonate catabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

D-glucuronate metabolic process [inference]

D-glucuronate catabolic process

galacturonate metabolic process [inference]

D-galacturonate metabolic process [inference]

D-galacturonate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate catabolic process

galacturonate catabolic process [inference]

D-galacturonate catabolic process

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

DNA damage response

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response

Displaying 1 entry
GO Term	Evidence Code	PMID
cytosol

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

Displaying **all 3** entries
GO Term	Evidence Code	PMID
2-dehydro-3-deoxygalactonokinase activity
2-dehydro-3-deoxygluconokinase activity
ATP binding

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

carbohydrate kinase activity [inference]

phosphotransferase activity, alcohol group as acceptor [inference]

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

Rhea

RHEA:14797

ATP + 2-dehydro-3-deoxy-D-gluconate

H⁺ + ADP + 2-dehydro-3-deoxy-6-phospho-D-gluconate

Enzyme

PMID

RHEA:16525

ATP + 2-dehydro-3-deoxy-D-galactonate

H⁺ + ADP + 2-dehydro-3-deoxy-6-phospho-D-galactonate

Enzyme

PMID

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlycoPOST

UniCarb-DR

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Acknowledgements