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MIRAGE
galactose-3-O-sulfotransferase 1

Summary
Gene Symbol
  • GAL3ST1
Aliases
  • CST
  • cerebroside (3' phosphoadenylylsulfate:galactosylceramide 3') sulfotransferase
Organism
Homo sapiens (human)
NCBI Gene
9514
GGDB ID
HGNC
24240
mRNA
map
  • 22q12.2
Protein
OMIM
KEGG Gene ID
hsa:9514
PubChem
9514
Alliance of Genome Resources
JoGo
GAL3ST1
TogoVar
GAL3ST1
Annotation
Keyword
  • Direct protein sequencing
  • Glycoprotein
  • Golgi apparatus
  • Proteomics identification
  • Reference proteome
  • Signal-anchor
  • Sphingolipid metabolism
  • Transferase
  • Transmembrane helix
Proteins
Displaying all 2 entries
UniProt Protein Name
Q99999
  • 3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase
  • 3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase
  • Cerebroside sulfotransferase
B2R7S4
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 8 in total
GO Term Evidence Code PMID
protein N-linked glycosylation
sphingolipid metabolic process
galactosylceramide metabolic process
galactosylceramide biosynthetic process
glycosphingolipid biosynthetic process
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
Galactose-3-O-sulfotransferase
Functional Category
  • E: Amino acid transport and metabolism
  • G: Carbohydrate transport and metabolism
  • T: Signal transduction mechanisms
Displaying all 3 entries
Gene Ontology
galactose 3-O-sulfotransferase activity
galactosylceramide sulfotransferase activity
glycolipid biosynthetic process
Displaying all 2 entries
InterPro
Galactose-3-O-sulfotransferase
P-loop containing nucleoside triphosphate hydrolase
GlycoGene Database (GGDB)
GGDB ID
gg041
Gene Symbol
  • GAL3ST1
Reactions
Displaying 1 entry
Donor Acceptor Reducing terminal(Acceptor) Reference
PAPS
G65889KE
Ceramide
Orthologous Gene
Displaying all 2 entries
Species Protein mRNA
Mus musculus NP_058618 NM_016922
Rattus norvegicus AAH87145 BC087145
KEGG BRITE Database
Orthology
K01019
Name
galactosylceramide sulfotransferase [EC:2.8.2.11]
References
Rhea

RHEA:41744

3'-phosphoadenylyl sulfate + a 1-O-alkyl-2-acyl-3-O-(β-D-galactosyl)-sn-glycerol
H+ + adenosine 3',5'-bisphosphate + a 1-O-alkyl-2-acyl-3-(β-D-3-sulfogalactosyl)-sn-glycerol
Enzyme
PMID

RHEA:20613

a β-D-galactosyl-(1↔1ʼ)-N-acylsphing-4-enine + 3'-phosphoadenylyl sulfate
H+ + adenosine 3',5'-bisphosphate + N-acyl-1-β-D-(3-O-sulfo)-galactosyl-sphing-4-enine
Enzyme
PMID
LIPID MAPS Gene / Proteome Database
LMPD ID
LMP002076
Gene Name
galactose-3-O-sulfotransferase 1
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026