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Fibroblast growth factor receptor

Summary

UniProt ID

A0A452S0V6

Gene Symbol

FGFR1

Organism

Ursus americanus (American black bear)

External Links

Annotation

Keyword

ATP-binding
Cell membrane
Cytoplasmic vesicle
Disulfide bond
Glycoprotein
Immunoglobulin domain
Nucleus
Phosphoprotein
Receptor
Reference proteome
Repeat
Tyrosine-protein kinase
Ubl conjugation

Gene Ontology (GO)

Displaying **all 9** entries
GO Term
phosphorylation
positive regulation of blood vessel endothelial cell migration
positive regulation of neuron differentiation
regulation of macromolecule metabolic process
positive regulation of vascular endothelial cell proliferation
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
positive regulation of endothelial cell chemotaxis to fibroblast growth factor
positive regulation of MAPK cascade
epithelial to mesenchymal transition

Displaying **all 5** entries
GO Term
cytoplasmic vesicle
receptor complex
cytosol
nucleus
plasma membrane

Displaying **all 6** entries
GO Term
heparin binding
protein homodimerization activity
fibroblast growth factor receptor activity
fibroblast growth factor binding
ATP binding
receptor-receptor interaction

Annotation information from UniProt.

Sequence

MSGKLGIQARISQSSSQRGQCPFATFSWGNRNALCLSPSSLSPLPAPSLGSSSRPPWVAAAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLVESNRTRITGEEVEVRDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIVIYCTGAFLISCMVGSVVVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSVPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	Source
107	N-linked (GlcNAc...) asparagine	UniProt
147	N-linked (GlcNAc...) asparagine	UniProt
255	N-linked (GlcNAc...) asparagine	UniProt
268	N-linked (GlcNAc...) asparagine	UniProt
292	N-linked (GlcNAc...) asparagine	UniProt
324	N-linked (GlcNAc...) asparagine	UniProt
345	N-linked (GlcNAc...) asparagine	UniProt
358	N-linked (GlcNAc...) asparagine	UniProt