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Fibroblast growth factor receptor

Summary

UniProt ID

A0A7N4PKV0

Gene Symbol

FGFR1

Organism

Sarcophilus harrisii (Tasmanian devil)

External Links

Annotation

Keyword

ATP-binding
Cell membrane
Cytoplasmic vesicle
Disulfide bond
Glycoprotein
Immunoglobulin domain
Nucleus
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Tyrosine-protein kinase
Ubl conjugation

Gene Ontology (GO)

Displaying entries **11 - 20** of 51 in total

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GO Term
positive regulation of vascular endothelial cell proliferation
positive regulation of stem cell proliferation
positive regulation of parathyroid hormone secretion
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
positive regulation of endothelial cell chemotaxis to fibroblast growth factor
regulation of extrinsic apoptotic signaling pathway in absence of ligand
ventricular zone neuroblast division
embryonic limb morphogenesis
regulation of lateral mesodermal cell fate specification

Displaying **all 5** entries
GO Term
receptor complex
cytosol
nucleus
plasma membrane
cytoplasmic vesicle

Displaying **all 7** entries
GO Term
protein homodimerization activity
fibroblast growth factor receptor activity
fibroblast growth factor binding
ATP binding
SH2 domain binding
receptor-receptor interaction
heparin binding

Annotation information from UniProt.

Sequence

MWSWKGLLFWAVLVTATLCTARPAPTLPEQARPWGAPVEVESSLVHPGDLLQLRCRLREDVQSINWLRDGVQLVESNRTRITGEEVEVRDAVPSDSGLYACVTNSPSGSDITYFSVNVSDALPSSEDDDDDDDSSSEEKESDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSNGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIIYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHAPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAIPSQRPTFKQLVEDLDRIVALTSNQEYLDLSVPLDQYSPSFPDTRSSTCSSGEDSVFSHDPLPEEPCLPRHPAPLANGGLKRR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	Source
77	N-linked (GlcNAc...) asparagine	UniProt
117	N-linked (GlcNAc...) asparagine	UniProt
225	N-linked (GlcNAc...) asparagine	UniProt
238	N-linked (GlcNAc...) asparagine	UniProt
262	N-linked (GlcNAc...) asparagine	UniProt
294	N-linked (GlcNAc...) asparagine	UniProt
315	N-linked (GlcNAc...) asparagine	UniProt
328	N-linked (GlcNAc...) asparagine	UniProt