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Fibroblast growth factor receptor

Summary

UniProt ID

A0A8C8Y440

Gene Symbol

FGFR2

Organism

Panthera leo (lion)

External Links

Annotation

Keyword

ATP-binding
Cell membrane
Disulfide bond
Glycoprotein
Immunoglobulin domain
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Tyrosine-protein kinase

Gene Ontology (GO)

Displaying **all 5** entries
GO Term
positive regulation of cell population proliferation
phosphorylation
negative regulation of keratinocyte proliferation
embryonic cranial skeleton morphogenesis
positive regulation of MAPK cascade

Displaying **all 7** entries
GO Term
receptor complex
cell cortex
collagen-containing extracellular matrix
nucleus
Golgi apparatus
plasma membrane
cell surface

Displaying **all 4** entries
GO Term
fibroblast growth factor receptor activity
fibroblast growth factor binding
ATP binding
protein homodimerization activity

Annotation information from UniProt.

Sequence

MVSWGRFLCLVVVTMATLALARPSFNLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLELRCPLRDATMISWTKDGVHLGPNNRTVLIGEYLQVKGATPRDSGLYACTAARPVDSEAVYFMVNVTDAISSGDDEDDTEGSEDFVSENNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPTPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYICKVSNYIGQANQSAWLTVLPKQQAPVREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKTTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKEKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHVNGSVKT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	Source
83	N-linked (GlcNAc...) asparagine	UniProt
123	N-linked (GlcNAc...) asparagine	UniProt
227	N-linked (GlcNAc...) asparagine	UniProt
240	N-linked (GlcNAc...) asparagine	UniProt
264	N-linked (GlcNAc...) asparagine	UniProt
296	N-linked (GlcNAc...) asparagine	UniProt
317	N-linked (GlcNAc...) asparagine	UniProt
328	N-linked (GlcNAc...) asparagine	UniProt