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Fibroblast growth factor receptor

Summary

UniProt ID

A0A8C9K9Q6

Gene Symbol

FGFR1

Organism

Panthera tigris altaica (Amur tiger)

External Links

Annotation

Keyword

ATP-binding
Cell membrane
Cytoplasmic vesicle
Disulfide bond
Glycoprotein
Immunoglobulin domain
Nucleus
Phosphoprotein
Receptor
Reference proteome
Repeat
Transmembrane helix
Tyrosine-protein kinase
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 51 in total

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GO Term
positive regulation of vascular endothelial cell proliferation
positive regulation of stem cell proliferation
positive regulation of parathyroid hormone secretion
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
positive regulation of endothelial cell chemotaxis to fibroblast growth factor
regulation of extrinsic apoptotic signaling pathway in absence of ligand
ventricular zone neuroblast division
embryonic limb morphogenesis
regulation of lateral mesodermal cell fate specification

Displaying **all 5** entries
GO Term
nucleus
plasma membrane
cytosol
cytoplasmic vesicle
receptor complex

Displaying **all 7** entries
GO Term
protein homodimerization activity
fibroblast growth factor receptor activity
fibroblast growth factor binding
heparin binding
ATP binding
SH2 domain binding
receptor-receptor interaction

Annotation information from UniProt.

Sequence

MEAGVSLKRRIKLKTESPWRCGAWSPTSNCRTGMWSWKYLLLAVLVTATLCTARPAPTLPEQAQPWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLVESNRTRITGEEVEVRDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIIYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	Source
109	N-linked (GlcNAc...) asparagine	UniProt
149	N-linked (GlcNAc...) asparagine	UniProt
257	N-linked (GlcNAc...) asparagine	UniProt
270	N-linked (GlcNAc...) asparagine	UniProt
294	N-linked (GlcNAc...) asparagine	UniProt
326	N-linked (GlcNAc...) asparagine	UniProt
347	N-linked (GlcNAc...) asparagine	UniProt
360	N-linked (GlcNAc...) asparagine	UniProt