Fibroblast growth factor receptor

Summary
UniProt ID
A0A8I3NNZ2
Gene Symbol
  • FGFR1
Organism
Canis lupus familiaris (dog)
Annotation
Keyword
  • ATP-binding
  • Cell membrane
  • Cytoplasmic vesicle
  • Disulfide bond
  • Glycoprotein
  • Immunoglobulin domain
  • Nucleus
  • Phosphoprotein
  • Receptor
  • Reference proteome
  • Repeat
  • Tyrosine-protein kinase
  • Ubl conjugation
Gene Ontology (GO)
Sequence
MEAGVSLKRKIKLRTESPWRCGAWSPTSNCRTGMWSWKCLLFWAVLVTATLCTARPAPTLPEQAQSWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLVESNRTRITGEEVEVRDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAAMTSPLYLEIIIYCTGAFLISCMVGSVIIYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSVPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR
Glycosylation Sites
Displaying all 8 entries
Position Description PubMed ID GlyTouCan ID Source
110 N-linked (GlcNAc...) asparagine
150 N-linked (GlcNAc...) asparagine
258 N-linked (GlcNAc...) asparagine
271 N-linked (GlcNAc...) asparagine
295 N-linked (GlcNAc...) asparagine
327 N-linked (GlcNAc...) asparagine
348 N-linked (GlcNAc...) asparagine
361 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying entries 1 - 10 of 13 in total
Pathway Name Organism
Downstream signaling of activated FGFR1 Canis familiaris
FGFR1b ligand binding and activation Canis familiaris
FGFR1c and Klotho ligand binding and activation Canis familiaris
FGFR1c ligand binding and activation Canis familiaris
FRS-mediated FGFR1 signaling Canis familiaris
Negative regulation of FGFR1 signaling Canis familiaris
PI-3K cascade:FGFR1 Canis familiaris
PI3K Cascade Canis familiaris
PI3K/AKT Signaling Canis familiaris
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Canis familiaris

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024