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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Fibroblast growth factor receptor
Summary
- UniProt ID
- A0A8I3NNZ2
- Gene Symbol
-
- FGFR1
- Organism
- Canis lupus familiaris (dog)
External Links
Annotation
- Keyword
-
- ATP-binding
- Cell membrane
- Cytoplasmic vesicle
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Nucleus
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| cytosol |
| nucleus |
| plasma membrane |
| cytoplasmic vesicle |
| receptor complex |
Sequence
MEAGVSLKRKIKLRTESPWRCGAWSPTSNCRTGMWSWKCLLFWAVLVTATLCTARPAPTLPEQAQSWGAPVEVESFLVHPGDLLQLRCRLRDDVQSINWLRDGVQLVESNRTRITGEEVEVRDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAAMTSPLYLEIIIYCTGAFLISCMVGSVIIYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSVPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 110 | N-linked (GlcNAc...) asparagine |
|
||
| 150 | N-linked (GlcNAc...) asparagine |
|
||
| 258 | N-linked (GlcNAc...) asparagine |
|
||
| 271 | N-linked (GlcNAc...) asparagine |
|
||
| 295 | N-linked (GlcNAc...) asparagine |
|
||
| 327 | N-linked (GlcNAc...) asparagine |
|
||
| 348 | N-linked (GlcNAc...) asparagine |
|
||
| 361 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Downstream signaling of activated FGFR1 | Canis familiaris |
| FGFR1b ligand binding and activation | Canis familiaris |
| FGFR1c and Klotho ligand binding and activation | Canis familiaris |
| FGFR1c ligand binding and activation | Canis familiaris |
| FRS-mediated FGFR1 signaling | Canis familiaris |
| Negative regulation of FGFR1 signaling | Canis familiaris |
| PI-3K cascade:FGFR1 | Canis familiaris |
| PI3K Cascade | Canis familiaris |
| PI3K/AKT Signaling | Canis familiaris |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Canis familiaris |
