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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Fibroblast growth factor receptor
Summary
- UniProt ID
- A0A8I3P6D2
- Gene Symbol
-
- FGFR2
- Organism
- Canis lupus familiaris (dog)
External Links
Annotation
- Keyword
-
- ATP-binding
- Cell membrane
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Transmembrane helix
- Tyrosine-protein kinase
- Gene Ontology (GO)
| GO Term |
|---|
| collagen-containing extracellular matrix |
| receptor complex |
| nucleus |
| Golgi apparatus |
| plasma membrane |
| cell cortex |
| cell surface |
| GO Term |
|---|
| fibroblast growth factor binding |
| ATP binding |
| protein homodimerization activity |
| fibroblast growth factor receptor activity |
Sequence
MGVTSTWRYGRGRGIGTAAAMVSWARFVCLAAVTMATLSLARPSFNLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLELRCLLRDAATIIWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTAARPVDSEAVYFMVNVTDAISSGDDEDDTDGSEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPTPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEEDAGEYICKVSNYIGQANQSAWLTVLPKQQAPVREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKTTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKEKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQKLKHAVSQTSGRLEQPRIEDPTNQPETSWSASSYCTAEVPEGESPEVSAVTTDQELVVPEGHLAGNGLSKAAASWSRWGIRTALDWFTP
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 103 | N-linked (GlcNAc...) asparagine |
|
||
| 143 | N-linked (GlcNAc...) asparagine |
|
||
| 248 | N-linked (GlcNAc...) asparagine |
|
||
| 261 | N-linked (GlcNAc...) asparagine |
|
||
| 285 | N-linked (GlcNAc...) asparagine |
|
||
| 317 | N-linked (GlcNAc...) asparagine |
|
||
| 338 | N-linked (GlcNAc...) asparagine |
|
||
| 349 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| FGFR2b ligand binding and activation | Canis familiaris |
| FGFR2c ligand binding and activation | Canis familiaris |
| FRS-mediated FGFR2 signaling | Canis familiaris |
| Negative regulation of FGFR2 signaling | Canis familiaris |
| PI-3K cascade:FGFR2 | Canis familiaris |
| PI3K Cascade | Canis familiaris |
| PI3K/AKT Signaling | Canis familiaris |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Canis familiaris |
| Phospholipase C-mediated cascade; FGFR2 | Canis familiaris |
| RAF/MAP kinase cascade | Canis familiaris |
