Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Neurogenic locus notch homolog protein 1
Summary
- UniProt ID
- A2RUV0
- Gene Symbol
-
- notch1
- Organism
- Xenopus tropicalis (tropical clawed frog)
External Links
Annotation
- Keyword
-
- ANK repeat
- Activator
- Angiogenesis
- Calcium
- Cell membrane
- Developmental protein
- Differentiation
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Metal-binding
- Notch signaling pathway
- Nucleus
- Receptor
- Reference proteome
- Repeat
- Signal
- Transcription regulation
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| plasma membrane |
| GO Term |
|---|
| calcium ion binding |
| signaling receptor activity |
| Notch binding |
Sequence
MYRIGLLVLIWSLLGLAQGLRCTQTAEMCLNGGRCEMTPGGTGVCLCSSSYFGERCQYPNPCALKNQCMNFGTCEPVLLGNAIDFTCHCPVGFTDKVCLTPVDNACVNNPCRNGGTCELLSSVSDYRCRCPPGWTGDSCQQADPCASNPCANGGKCLPFETQYICKCPSGFHGATCKQDINECSQNPCRNGGQCLNEFGSYRCNCQNRFTGRNCEEPYVPCNPSPCLNGGTCRQTDDTSYECTCLPGFSGQNCEENIDDCPSNNCRNGGTCVDGVNTYNCQCPPDWTGQYCTEDVDECQLMPNACQNGGTCHNTYGGYNCVCVNGWTGEDCSENIDDCANAACHSGATCHDRVASFFCECPHGRTGLLCHLDNACISNPCNEGSNCDTNPVNGKAICTCPPGYTGPACNNDVDECSLGANPCEHGGRCTNTLGSFQCNCPQGYAGPRCEIDVNECLSNPCQNDATCLDQIGEFQCICMPGYEGLYCETNIDECASNPCLHNGKCVDKINEFHCECPTGFNGNLCQHDVDECASTPCKNGAKCLDGPNSYTCQCTEGFTGRHCEQDINECIPDPCHYGTCKDGIATFTCLCRPGYTGRLCDNDINECLSQPCQNGGQCTDRENGYICTCPKGTTGVNCETNLDDCASNPCDYGKCIDKIDGYECTCEPGYTGKMCNINIDECASNPCRNGGTCKDKINGFTCVCPDGYHDHMCLSEVNECNSNPCIHGTCHDGINGYKCDCDAGWSGSNCDVNNNECESNPCMNGGTCKDMTGAYICTCRAGFSGPNCQTNINECASNPCLNRGTCIDDVAGYKCNCMLPYTGAICEAVLAPCSGSPCKNGGRCKESEDYETFSCECPPGWQGQTCEIDMNECVNRPCRNGAMCQNTNGSYKCNCKPGYAGRHCETDIDDCQPNPCHNGGSCSDGINMFFCNCPAGFRGPKCEEDINECASNPCKNGANCTDCVNSYTCTCQPGFSGIHCENNTPDCTESSCFNGGTCIDGINTFSCQCPPGFTGNYCQHDINECDSKPCLNGGTCQDSYGAYKCTCPQGYTGLNCQNLVRWCDSSPCKNGGKCWQTNNFYRCECKSGWTGVYCDVPSVSCEVAAKQQGVDIAHLCRNSGMCVDTGNTHFCRCQAGYTGSYCEEQVDECSPNPCQNGATCTDYLGGYSCECVAGYHGVNCSEEINECLSHPCHNGGTCIDLINTYKCSCPRGTQGVHCEINVDDCTPFYDSVSLEPKCFNNGKCFDRVGGYNCICPPGFVGERCEGDVNECLSNPCDPRGTQNCIQLVNDYRCECRQGFTGRRCDSVVDGCKGLPCRNGGTCAVASNTERGFICKCPPGFDGATCEYDARTCGNLRCQNGGTCISVLKSSKCVCSEGYTGATCQYPVVSPCASRPCYNGGTCQFSPEEPFFQCFCPTNFNGLFCHILDYGFIGGLGKNITPPDNEEICENEQCAELADNKICNANCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFNDGKCDSQCNNSGCLYDGFDCQKVEVQCNPLYDQYCRDHFQDGHCDQGCNNAECEWDGLDCDNMPENLAEGTLLIVVLMPPEKLKNNSVNFLRELSRVLHTNVVFKKDSKGEYKIYPYYGNEEELKKHHIKKRSAASWSDAPTAIFSTMKESVLPGRRRRELDQMEVRGSIVYLEIDNRQCYKSSSQCFTSATDVAAFLGALATHGNLNIPYKIEAVKSEIVETAKPPPPLYAMFSMLVIPLLIIFVIMVVIVNKKRRREHGQLWFPEGFIPKEPSKKKRREPLGEDSVGLKPLKNLTDGSFMDDNQNEWGDEETLENKRFRFEEQVMLPELVDDQTDHRQWTQQHLDAADLRIPSMAPTPPQGEIDADCMDVNVRGPDGFTPLMIAACSGGGLETGNSEEEEDASANMISDFIGQGAQLHNQTDRTGETALHLAARYARADAAKRLLESSADANVPDNMGRTPLHAAVAADAQGVFQILIRNRATDLDARMCDGTTPLILAARLAVEGMVEELINAHADVNAVDEFGKSALHWAAAVNNVDAAAVLLKSSANKDMQNNKEETPLFLAAREGSYETAKVLLDHYANRDITDHMDRLPRDIAQERMHHDIVHLLDEHNLVKSPTLHGGPLGAPTLSPPICSPNGYMGNMKPSVQSKKARKPSIKGNGCKEAKELKARRKKSQDGKTSLLDSGSSGVLSPVDSLESPHGYLSDVASPPLMTSPFQQSPSMPLNHLTSMQDSHLGLNHMTMANKQEMASNRMAFDGMTPRLTHLNVSSPNTIMTNGSMHFTVGGAPAMNGQCDWFARLQNGMVQNQYNPIRNGIQQGNAQQALQHGLMSSLHNGLPATTLSQMMTYQAMPNTRMANQPHLMQAQQMQQQQNLQLHQSVQQQQHQNSNATSTHIGSPFCSNDISQTDLQQMSGNNIHSVMPQDTQIFTNSLPPTLTQSMATTQFLTPPSQHSYSSPMDNTPSHQLQVPDHPFLTPSPESPDQWSSSSPHSNMSDWSEGISSPPTSMQPQRTHIPEAFK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 231 | O-linked (GalNAc...) threonine; alternate |
|
||
| 434 | O-linked (Glc...) serine |
|
||
| 457 | O-linked (Glc...) serine |
|
||
| 465 | O-linked (Fuc...) threonine |
|
||
| 495 | O-linked (Glc...) serine |
|
||
| 887 | N-linked (GlcNAc...) asparagine |
|
||
| 958 | N-linked (GlcNAc...) asparagine |
|
||
| 1178 | N-linked (GlcNAc...) asparagine |
|
||
| 1400 | O-linked (GalNAc...) threonine; alternate |
|
||
| 1487 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activated NOTCH1 Transmits Signal to the Nucleus | Xenopus tropicalis |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | Xenopus tropicalis |
| NOTCH2 intracellular domain regulates transcription | Xenopus tropicalis |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | Xenopus tropicalis |
| Noncanonical activation of NOTCH3 | Xenopus tropicalis |
| Pre-NOTCH Processing in Golgi | Xenopus tropicalis |
