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Homeobox protein Nkx-2.6

Summary

UniProt ID

A6NCS4

Gene Symbol

NKX2-6
NKX2F

Organism

Homo sapiens (human)

External Links

GlyGen: A6NCS4
PubChem: A6NCS4
The O-GlcNAc Database: A6NCS4

Annotation

Keyword

Activator
DNA-binding
Developmental protein
Disease variant
Homeobox
Nucleus
Reference proteome
Transcription regulation

Gene Ontology (GO)

Displaying entries **1 - 10** of 18 in total

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GO Term
hypothalamus development
negative regulation of apoptotic process
tongue development
atrial cardiac muscle cell development
pharyngeal system development
epithelial cell apoptotic process
negative regulation of epithelial cell apoptotic process
ventricular cardiac muscle cell development
regulation of transcription by RNA polymerase II
positive regulation of transcription by RNA polymerase II

Displaying **all 2** entries
GO Term
chromatin
nucleus

Displaying **all 4** entries
GO Term
DNA-binding transcription factor activity, RNA polymerase II-specific
DNA-binding transcription activator activity, RNA polymerase II-specific
DNA-binding transcription factor activity
RNA polymerase II cis-regulatory region sequence-specific DNA binding

Annotation information from UniProt.

Sequence

MLLSPVTSTPFSVKDILRLERERSCPAASPHPRVRKSPENFQYLRMDAEPRGSEVHNAGGGGGDRKLDGSEPPGGPCEAVLEMDAERMGEPQPGLNAASPLGGGTRVPERGVGNSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQRQDKSLELAGHPLTPRRVAVPVLVRDGKPCLGPGPGAPAFPSPYSAAVSPYSCYGGYSGAPYGAGYGTCYAGAPSGPAPHTPLASAGFGHGGQNATPQGHLAATLQGVRAW

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites