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Toll-like receptor 7

Summary

UniProt ID

B3Y653

Gene Symbol

TLR7

Organism

Macaca mulatta (Rhesus monkey)

External Links

Annotation

Keyword

3D-structure
Calcium
Glycoprotein
Inflammatory response
Innate immunity
Leucine-rich repeat
Metal-binding
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 20 in total

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GO Term
positive regulation of transcription by RNA polymerase II
inflammatory response
positive regulation of chemokine production
positive regulation of type II interferon production
innate immune response
defense response to virus
regulation of protein phosphorylation
toll-like receptor signaling pathway
positive regulation of interferon-alpha production
positive regulation of interferon-beta production

Displaying **all 6** entries
GO Term
endosome
endoplasmic reticulum
lysosome
plasma membrane
receptor complex
early phagosome

Displaying **all 5** entries
GO Term
pattern recognition receptor activity
metal ion binding
double-stranded RNA binding
single-stranded RNA binding
siRNA binding

Annotation information from UniProt.

Sequence

MMFPVWTLKRQILILFNIILISKLLGARWFPKTLPCDVTLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRCNCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQGLPPSLQLLSLEANNIFSIRKENLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNLNQLQILDLSGNCPRCYNAPFPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFNLSPLHNLQNLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKISPSGDSSEVGFCSNARTSVESYEPQVLEQLYYFRYDKYARSCRFKNKEASFTSVNESCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSNSHYFQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRYLKNLETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLKMLLLHHNRFLCTCDAVWFVWWVNHTEVTIPYLATDVTCVGPGAHKGQSVISLDLYTCELDLTNLILFSLSISVSLFLMVMMTASHLYFWDVWYIYHFCKAKIKGYQRLISPDCCYDAFIVYDTKDPAVTEWVLAELVAKLEDPREKHFNLCLEERDWLPGQPVLENLSQSIQLSKKTVFVMTDKYAKTENFKIAFYLSHQRLMDEKVDVIILIFLEKPFQKSKFLQLRKRLCGSSVLEWPTNPQAHPYFWQCLKNALATDNHVAYSQVFKETV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 35 in total

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Position	Description	Source
66	N-linked (GlcNAc...) asparagine	UniProt
69	N-acetyl-D-glucosamine 2	UniProt
90	N-acetyl-D-glucosamine 1	UniProt
92	N-acetyl-D-glucosamine 2	UniProt
93	N-acetyl-D-glucosamine 3	UniProt
131	N-acetyl-D-glucosamine 3	UniProt
189	N-acetyl-D-glucosamine 4	UniProt
190	N-acetyl-D-glucosamine 4	UniProt
215	N-acetyl-D-glucosamine 4	UniProt
328	N-acetyl-D-glucosamine 5	UniProt