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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Hyaluronan synthase 3
Summary
- UniProt ID
- O00219
- Gene Symbol
-
- HAS3
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- O00219
- The Human Metabolome Database
- HMDBP01708
- The O-GlcNAc Database
- O00219
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Endosome
- Glycoprotein
- Glycosyltransferase
- Golgi apparatus
- Reference proteome
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| early endosome |
| hyaluranon cable |
| Golgi membrane |
| nucleus |
| Golgi apparatus |
| plasma membrane |
| membrane |
| GO Term |
|---|
| hyaluronan synthase activity |
| identical protein binding |
Sequence
MPVQLTTALRVVGTSLFALAVLGGILAAYVTGYQFIHTEKHYLSFGLYGAILGLHLLIQSLFAFLEHRRMRRAGQALKLPSPRRGSVALCIAAYQEDPDYLRKCLRSAQRISFPDLKVVMVVDGNRQEDAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQEGMDRVRDVVRASTFSCIMQKWGGKREVMYTAFKALGDSVDYIQVCDSDTVLDPACTIEMLRVLEEDPQVGGVGGDVQILNKYDSWISFLSSVRYWMAFNVERACQSYFGCVQCISGPLGMYRNSLLQQFLEDWYHQKFLGSKCSFGDDRHLTNRVLSLGYRTKYTARSKCLTETPTKYLRWLNQQTRWSKSYFREWLYNSLWFHKHHLWMTYESVVTGFFPFFLIATVIQLFYRGRIWNILLFLLTVQLVGIIKATYACFLRGNAEMIFMSLYSLLYMSSLLPAKIFAIATINKSGWGTSGRKTIVVNFIGLIPVSIWVAVLLGGLAYTAYCQDLFSETELAFLVSGAILYGCYWVALLMLYLAIIARRCGKKPEQYSLAFAEV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 462 | N-linked (GlcNAc...) asparagine |
|
||
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Hyaluronan biosynthesis and export | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:5675 | cribriform carcinoma | |
| DOID:6432 | pulmonary hypertension | |
| DOID:657 | adenoma | |
| DOID:684 | hepatocellular carcinoma | |
| DOID:7148 | rheumatoid arthritis | |
| DOID:769 | neuroblastoma | |
| DOID:8923 | skin melanoma | |
| DOID:9256 | colorectal cancer | |
| DOID:9351 | diabetes mellitus | |
| DOID:9352 | type 2 diabetes mellitus |
