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Lysosomal alpha-mannosidase

Summary

UniProt ID

O00754

Gene Symbol

MAN2B1
LAMAN
MANB

Organism

Homo sapiens (human)

External Links

GlycoProtDB

GPDB0011174

GlyConnect

GlyGen

O00754

PubChem

O00754

The Human Metabolome Database

HMDBP11810

The O-GlcNAc Database

O00754

RaftProt

O00754

O-GlcNAcAtlas

O00754

Annotation

Keyword

Alternative splicing
Direct protein sequencing
Disease variant
Disulfide bond
Glycoprotein
Glycosidase
Lysosome
Metal-binding
Reference proteome
Signal
Zinc
Zymogen

Gene Ontology (GO)

Displaying **all 6** entries
GO Term
learning or memory
protein modification process
protein deglycosylation
mannose metabolic process
N-glycan processing
oligosaccharide catabolic process

Displaying **all 9** entries
GO Term
Golgi membrane
extracellular region
extracellular space
lysosome
intracellular membrane-bounded organelle
extracellular exosome
nucleoplasm
azurophil granule lumen
lysosomal lumen

Displaying **all 3** entries
GO Term
metal ion binding
carbohydrate binding
alpha-mannosidase activity

Annotation information from UniProt.

Sequence

MGAYARASGVCARGCLDSAGPWTMSRALRPPLPPLCFFLLLLAAAGARAGGYETCPTVQPNMLNVHLLPHTHDDVGWLKTVDQYFYGIKNDIQHAGVQYILDSVISALLADPTRRFIYVEIAFFSRWWHQQTNATQEVVRDLVRQGRLEFANGGWVMNDEAATHYGAIVDQMTLGLRFLEDTFGNDGRPRVAWHIDPFGHSREQASLFAQMGFDGFFFGRLDYQDKWVRMQKLEMEQVWRASTSLKPPTADLFTGVLPNGYNPPRNLCWDVLCVDQPLVEDPRSPEYNAKELVDYFLNVATAQGRYYRTNHTVMTMGSDFQYENANMWFKNLDKLIRLVNAQQAKGSSVHVLYSTPACYLWELNKANLTWSVKHDDFFPYADGPHQFWTGYFSSRPALKRYERLSYNFLQVCNQLEALVGLAANVGPYGSGDSAPLNEAMAVLQHHDAVSGTSRQHVANDYARQLAAGWGPCEVLLSNALARLRGFKDHFTFCQQLNISICPLSQTAARFQVIVYNPLGRKVNWMVRLPVSEGVFVVKDPNGRTVPSDVVIFPSSDSQAHPPELLFSASLPALGFSTYSVAQVPRWKPQARAPQPIPRRSWSPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIGDNESDQASGAYIFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLYPGQRHLELEWSVGPIPVGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQTEPVAGNYYPVNTRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDGRGVSEPLMENGSGAWVRGRHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLAPGGGAAYNLGAPPRTQFSGLRRDLPPSVHLLTLASWGPEMVLLRLEHQFAVGEDSGRNLSAPVTLNLRDLFSTFTITRLQETTLVANQLREAASRLKWTTNTGPTPHQTPYQLDPANITLEPMEIRTFLASVQWKEVDG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 15 in total

1

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Position	Description	PubMed ID	GlyTouCan ID	Source
133	N-linked (GlcNAc...) asparagine		G45395BF G08290VR G47644PP G92275SC	UniProt GlyGen
310	N-linked (GlcNAc...) asparagine		G41247ZX G02815KT G28681TP	UniProt GlyGen
367	N-linked (GlcNAc...) asparagine	19159218	G82443XX G46691LC G83460ZZ G80920RR G62765YT G05724UK G31852PQ G90575OW G39188ZX G41247ZX G50282JC G02815KT G06110VR G14669DU	UniProt GlyGen GlyConnect
371			G49108TO	GlyGen
497	N-linked (GlcNAc...) asparagine		G80920RR G14669DU G28681TP	UniProt GlyGen GlyConnect
645	N-linked (GlcNAc...) asparagine		G77277QT	UniProt GlyGen
651	N-linked (GlcNAc...) asparagine		G31852PQ G41247ZX	UniProt GlyGen
692	N-linked (GlcNAc...) asparagine		G08918WF G00912UN G48414YA G41071NU G59626AS G08290VR G20210JR G23294PN G80920RR G01485JJ G65184UU G42124LM G02886BB G72790NZ G10486CT G90734RJ G85269DF G72291OX G95865ZB G05724UK G31852PQ G49955PK G72787SB G41247ZX G35029YA G57776ZU G02815KT G06110VR G57317CE G92050GC G14669DU G28681TP	UniProt GlyGen GlyConnect
766	N-linked (GlcNAc...) asparagine	19159218	G45395BF G08918WF G00912UN G27058EU G41071NU G08290VR G01650EU G80920RR G42124LM G12313PD G29299MO G37399XV G82463GQ G62765YT G47950XN G62894KT G11870QZ G47644PP G05049YU G55383ZG G72291OX G95865ZB G31852PQ G11314AS G41247ZX G02815KT G74724QE G92275SC	GlycoProtDB UniProt GlyGen GlyConnect
774				GlyGen