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Cyclin-dependent kinase inhibitor 1B

Summary

UniProt ID

O08769

Gene Symbol

Cdkn1b
p27Kip1

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: O08769
The O-GlcNAc Database: O08769
O-GlcNAcAtlas: O08769

Annotation

Keyword

Cytoplasm
Endosome
Nucleus
Phosphoprotein
Protein kinase inhibitor
Proteomics identification
Reference proteome
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 46 in total

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GO Term
placenta development
positive regulation of protein phosphorylation
apoptotic process
regulation of mitotic cell cycle
heart development
sensory perception of sound
positive regulation of cell population proliferation
negative regulation of cell population proliferation
regulation of cell migration
negative regulation of phosphorylation

Displaying **all 7** entries
GO Term
nucleus
cytoplasm
protein-containing complex
Cul4A-RING E3 ubiquitin ligase complex
cytosol
nucleoplasm
endosome

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GO Term
cyclin-dependent protein serine/threonine kinase inhibitor activity
protein phosphatase binding
protein kinase inhibitor activity
protein-containing complex binding
protein kinase binding
molecular adaptor activity
protein-folding chaperone binding
ubiquitin ligase activator activity
cyclin-dependent protein kinase activating kinase regulator activity
cyclin binding

Annotation information from UniProt.

Sequence

MSNVRVSNGSPSLERMDARQTEHPKPSACRNLFGPVNHEELTRDLEKHCRDMEEASQRKWNFDFQNHKPLEGRYEWQEVERGSLPEFYYRPPRPPKSACKVPAQESLDVSGSRQAVPSIGSQANSEDRHLVDQMPDSSDSPAGLAEQCPGMRKRPAAEDSSSQNKRANRTEENVSDGSPNAGTVEQTPKKPGLRRQT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	GlyTouCan ID	Source
2	G49108TO	GlyGen The O-GlcNAc Database
110	G49108TO	GlyGen The O-GlcNAc Database
197	G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **1 - 10** of 11 in total

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Pathway Name	Organism
AKT phosphorylates targets in the cytosol	Rattus norvegicus
Cyclin A:Cdk2-associated events at S phase entry	Rattus norvegicus
Cyclin D associated events in G1	Rattus norvegicus
Cyclin E associated events during G1/S transition	Rattus norvegicus
DNA Damage/Telomere Stress Induced Senescence	Rattus norvegicus
Estrogen-dependent nuclear events downstream of ESR-membrane signaling	Rattus norvegicus
PTK6 Regulates Cell Cycle	Rattus norvegicus
SCF(Skp2)-mediated degradation of p27/p21	Rattus norvegicus
Senescence-Associated Secretory Phenotype (SASP)	Rattus norvegicus
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest	Rattus norvegicus