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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3
Summary
- UniProt ID
- O14638
- Gene Symbol
-
- ENPP3
- PDNP3
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011176
- GlyGen
- O14638
- PubChem
- O14638
- The Human Metabolome Database
- HMDBP00194
- RaftProt
- O14638
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Cell membrane
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Hydrolase
- Metal-binding
- Reference proteome
- Repeat
- Secreted
- Signal-anchor
- Transmembrane helix
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| external side of plasma membrane |
| perinuclear region of cytoplasm |
| extracellular exosome |
| apical plasma membrane |
| GO Term |
|---|
| phosphodiesterase I activity |
| nucleoside triphosphate diphosphatase activity |
| zinc ion binding |
| nucleic acid binding |
| calcium ion binding |
Sequence
MESTLTLATEQPVKKNTLKKYKIACIVLLALLVIMSLGLGLGLGLRKLEKQGSCRKKCFDASFRGLENCRCDVACKDRGDCCWDFEDTCVESTRIWMCNKFRCGETRLEASLCSCSDDCLQRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGFDLPPVILFSMDGFRAEYLYTWDTLMPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVNLNKNFSLSSKEQNNPAWWHGQPMWLTAMYQGLKAATYFWPGSEVAINGSFPSIYMPYNGSVPFEERISTLLKWLDLPKAERPRFYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQRNLHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINFFYMYEGPAPRIRAHNIPHDFFSFNSEEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNVRIDKVHLFVDQQWLAVRSKSNTNCGGGNHGYNNEFRSMEAIFLAHGPSFKEKTEVEPFENIEVYNLMCDLLRIQPAPNNGTHGSLNHLLKVPFYEPSHAEEVSKFSVCGFANPLPTESLDCFCPHLQNSTQLEQVNQMLNLTQEEITATVKVNLPFGRPRVLQKNVDHCLLYHREYVSGFGKAMRMPMWSSYTVPQLGDTSPLPPTVPDCLRADVRVPPSESQKCSFYLADKNITHGFLYPPASNRTSDSQYDALITSNLVPMYEEFRKMWDYFHSVLLIKHATERNGVNVVSGPIFDYNYDGHFDAPDEITKHLANTDVPIPTHYFVVLTSCKNKSHTPENCPGWLDVLPFIIPHRPTNVESCPEGKPEALWVEERFTAHIARVRDVELLTGLDFYQDKVQPVSEILQLKTYLPTFETTI
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 236 | N-linked (GlcNAc...) asparagine | |||
| 279 | N-linked (GlcNAc...) asparagine |
|
||
| 290 | N-linked (GlcNAc...) asparagine |
|
||
| 426 | N-linked (GlcNAc...) asparagine |
|
||
| 532 |
|
|
||
| 533 | N-linked (GlcNAc...) asparagine | |||
| 540 |
|
|
||
| 582 | N-linked (GlcNAc...) asparagine |
|
||
| 594 | N-linked (GlcNAc...) asparagine |
|
||
| 619 |
|
|
G80920RR
G15664MX
G83460ZZ
G62765YT
G31852PQ
G54010QB
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Vitamin B5 (pantothenate) metabolism | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3571 | liver cancer | |
| DOID:0060250 | idiopathic scoliosis | |
| DOID:11432 | endometriosis of ovary | |
| DOID:12309 | urticaria pigmentosa | |
| DOID:1520 | colon carcinoma | |
| DOID:162 | cancer | |
| DOID:2021 | placenta cancer | |
| DOID:219 | colon cancer | |
| DOID:235 | colonic benign neoplasm | |
| DOID:288 | endometriosis of uterus |
