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Ras-specific guanine nucleotide-releasing factor 2
Summary
- UniProt ID
- O14827
- Gene Symbol
-
- RASGRF2
- GRF2
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- O14827
- PubChem
- O14827
- The Human Metabolome Database
- HMDBP07970
- The O-GlcNAc Database
- O14827
- O-GlcNAcAtlas
- O14827
Annotation
- Keyword
-
- Calcium
- Calmodulin-binding
- Cell membrane
- Coiled coil
- Cytoplasm
- Endoplasmic reticulum
- Guanine-nucleotide releasing factor
- Phosphoprotein
- Reference proteome
- Repeat
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| cytosol |
| endoplasmic reticulum |
| endoplasmic reticulum membrane |
| GO Term |
|---|
| guanyl-nucleotide exchange factor activity |
| calmodulin binding |
Sequence
MQKSVRYNEGHALYLAFLARKEGTKRGFLSKKTAEASRWHEKWFALYQNVLFYFEGEQSCRPAGMYLLEGCSCERTPAPPRAGAGQGGVRDALDKQYYFTVLFGHEGQKPLELRCEEEQDGKEWMEAIHQASYADILIEREVLMQKYIHLVQIVETEKIAANQLRHQLEDQDTEIERLKSEIIALNKTKERMRPYQSNQEDEDPDIKKIKKVQSFMRGWLCRRKWKTIVQDYICSPHAESMRKRNQIVFTMVEAESEYVHQLYILVNGFLRPLRMAASSKKPPISHDDVSSIFLNSETIMFLHEIFHQGLKARIANWPTLILADLFDILLPMLNIYQEFVRNHQYSLQVLANCKQNRDFDKLLKQYEANPACEGRMLETFLTYPMFQIPRYIITLHELLAHTPHEHVERKSLEFAKSKLEELSRVMHDEVSDTENIRKNLAIERMIVEGCDILLDTSQTFIRQGSLIQVPSVERGKLSKVRLGSLSLKKEGERQCFLFTKHFLICTRSSGGKLHLLKTGGVLSLIDCTLIEEPDASDDDSKGSGQVFGHLDFKIVVEPPDAAAFTVVLLAPSRQEKAAWMSDISQCVDNIRCNGLMTIVFEENSKVTVPHMIKSDARLHKDDTDICFSKTLNSCKVPQIRYASVERLLERLTDLRFLSIDFLNTFLHTYRIFTTAAVVLGKLSDIYKRPFTSIPVRSLELFFATSQNNRGEHLVDGKSPRLCRKFSSPPPLAVSRTSSPVRARKLSLTSPLNSKIGALDLTTSSSPTTTTQSPAASPPPHTGQIPLDLSRGLSSPEQSPGTVEENVDNPRVDLCNKLKRSIQKAVLESAPADRAGVESSPAADTTELSPCRSPSTPRHLRYRQPGGQTADNAHCSVSPASAFAIATAAAGHGSPPGFNNTERTCDKEFIIRRTATNRVLNVLRHWVSKHAQDFELNNELKMNVLNLLEEVLRDPDLLPQERKAAANILRALSQDDQDDIHLKLEDIIQMTDCMKAECFESLSAMELAEQITLLDHVIFRSIPYEEFLGQGWMKLDKNERTPYIMKTSQHFNDMSNLVASQIMNYADVSSRANAIEKWVAVADICRCLHNYNGVLEITSALNRSAIYRLKKTWAKVSKQTKALMDKLQKTVSSEGRFKNLRETLKNCNPPAVPYLGMYLTDLAFIEEGTPNFTEEGLVNFSKMRMISHIIREIRQFQQTSYRIDHQPKVAQYLLDKDLIIDEDTLYELSLKIEPRLPA
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 761 |
|
|||
| 915 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CDC42 GTPase cycle | Homo sapiens |
| G alpha (12/13) signalling events | Homo sapiens |
| NRAGE signals death through JNK | Homo sapiens |
| RAC1 GTPase cycle | Homo sapiens |
| RAF/MAP kinase cascade | Homo sapiens |
| RHOA GTPase cycle | Homo sapiens |
| Ras activation upon Ca2+ influx through NMDA receptor | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
