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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Free fatty acid receptor 1
Summary
- UniProt ID
- O14842
- Gene Symbol
-
- FFAR1
- GPR40
- Organism
- Homo sapiens (human)
External Links
- PubChem
- O14842
- SwissLipids
- The Human Metabolome Database
- HMDBP02036
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Lipid-binding
- Reference proteome
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| GO Term |
|---|
| G protein-coupled receptor activity |
| lipid binding |
| bioactive lipid receptor activity |
Sequence
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 155 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion | Homo sapiens |
| Free fatty acid receptors | Homo sapiens |
| G alpha (q) signalling events | Homo sapiens |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | Homo sapiens |
| Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) | Homo sapiens |
