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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Aurora kinase A
Summary
- UniProt ID
- O14965
- Gene Symbol
-
- AURKA
- AIK
- AIRK1
- ARK1
- AURA
- AYK1
- BTAK
- IAK1
- STK15
- STK6
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- O14965
- PubChem
- O14965
- The Human Metabolome Database
- HMDBP01317
- The O-GlcNAc Database
- O14965
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Cell membrane
- Cilium
- Cilium biogenesis/degradation
- Cytoskeleton
- Isopeptide bond
- Microtubule
- Mitosis
- Phosphoprotein
- Proto-oncogene
- Reference proteome
- Serine/threonine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| positive regulation of mitochondrial fission |
| liver regeneration |
| GO Term |
|---|
| chromosome passenger complex |
| perinuclear region of cytoplasm |
| meiotic spindle |
| mitotic spindle pole |
| nucleus |
| microtubule cytoskeleton |
| pronucleus |
| germinal vesicle |
| glutamatergic synapse |
| spindle midzone |
Sequence
MDRSKENCISGPVKATAPVGGPKRVLVTQQFPCQNPLPVNSGQAQRVLCPSNSSQRIPLQAQKLVSSHKPVQNQKQKQLQATSVPHPVSRPLNNTQKSKQPLPSAPENNPEEELASKQKNEESKKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | Homo sapiens |
| AURKA Activation by TPX2 | Homo sapiens |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | Homo sapiens |
| Interaction between PHLDA1 and AURKA | Homo sapiens |
| Regulation of PLK1 Activity at G2/M Transition | Homo sapiens |
| Regulation of TP53 Activity through Phosphorylation | Homo sapiens |
| SUMOylation of DNA replication proteins | Homo sapiens |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | Homo sapiens |
