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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Glutamate receptor ionotropic, NMDA 2D
Summary
- UniProt ID
- O15399
- Gene Symbol
-
- GRIN2D
- GluN2D
- NMDAR2D
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- O15399
- PubChem
- O15399
- The Human Metabolome Database
- HMDBP01645
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Cell membrane
- Disease variant
- Disulfide bond
- Epilepsy
- Glycoprotein
- Ligand-gated ion channel
- Magnesium
- Methylation
- Phosphoprotein
- Postsynaptic cell membrane
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| regulation of synaptic plasticity |
| regulation of neuronal synaptic plasticity |
| startle response |
| ionotropic glutamate receptor signaling pathway |
| brain development |
| adult locomotory behavior |
| cellular response to L-glutamate |
Sequence
MRGAGGPRGPRGPAKMLLLLALACASPFPEEAPGPGGAGGPGGGLGGARPLNVALVFSGPAYAAEAARLGPAVAAAVRSPGLDVRPVALVLNGSDPRSLVLQLCDLLSGLRVHGVVFEDDSRAPAVAPILDFLSAQTSLPIVAVHGGAALVLTPKEKGSTFLQLGSSTEQQLQVIFEVLEEYDWTSFVAVTTRAPGHRAFLSYIEVLTDGSLVGWEHRGALTLDPGAGEAVLSAQLRSVSAQIRLLFCAREEAEPVFRAAEEAGLTGSGYVWFMVGPQLAGGGGSGAPGEPPLLPGGAPLPAGLFAVRSAGWRDDLARRVAAGVAVVARGAQALLRDYGFLPELGHDCRAQNRTHRGESLHRYFMNITWDNRDYSFNEDGFLVNPSLVVISLTRDRTWEVVGSWEQQTLRLKYPLWSRYGRFLQPVDDTQHLTVATLEERPFVIVEPADPISGTCIRDSVPCRSQLNRTHSPPPDAPRPEKRCCKGFCIDILKRLAHTIGFSYDLYLVTNGKHGKKIDGVWNGMIGEVFYQRADMAIGSLTINEERSEIVDFSVPFVETGISVMVARSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAVTVFIFEYLSPVGYNRSLATGKRPGGSTFTIGKSIWLLWALVFNNSVPVENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEEYVDTVSGLSDRKFQRPQEQYPPLKFGTVPNGSTEKNIRSNYPDMHSYMVRYNQPRVEEALTQLKAGKLDAFIYDAAVLNYMARKDEGCKLVTIGSGKVFATTGYGIALHKGSRWKRPIDLALLQFLGDDEIEMLERLWLSGICHNDKIEVMSSKLDIDNMAGVFYMLLVAMGLSLLVFAWEHLVYWRLRHCLGPTHRMDFLLAFSRGMYSCCSAEAAPPPAKPPPPPQPLPSPAYPAPRPAPGPAPFVPRERASVDRWRRTKGAGPPGGAGLADGFHRYYGPIEPQGLGLGLGEARAAPRGAAGRPLSPPAAQPPQKPPPSYFAIVRDKEPAEPPAGAFPGFPSPPAPPAAAATAVGPPLCRLAFEDESPPAPARWPRSDPESQPLLGPGAGGAGGTGGAGGGAPAAPPPCRAAPPPCPYLDLEPSPSDSEDSESLGGASLGGLEPWWFADFPYPYAERLGPPPGRYWSVDKLGGWRAGSWDYLPPRSGPAAWHCRHCASLELLPPPRHLSCSHDGLDGGWWAPPPPPWAAGPLPRRRARCGCPRSHPHRPRASHRTPAAAAPHHHRHRRAAGGWDLPPPAPTSRSLEDLSSCPRAAPARRLTGPSRHARRCPHAAHWGPPLPTASHRRHRGGDLGTRRGSAHFSSLESEV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 92 | N-linked (GlcNAc...) asparagine |
|
||
| 352 | N-linked (GlcNAc...) asparagine |
|
||
| 366 | N-linked (GlcNAc...) asparagine |
|
||
| 384 | N-linked (GlcNAc...) asparagine |
|
||
| 467 | N-linked (GlcNAc...) asparagine | |||
| 569 | N-linked (GlcNAc...) asparagine |
|
||
| 715 | N-linked (GlcNAc...) asparagine |
G70441OD
G80920RR
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Assembly and cell surface presentation of NMDA receptors | Homo sapiens |
| Long-term potentiation | Homo sapiens |
| Negative regulation of NMDA receptor-mediated neuronal transmission | Homo sapiens |
| Neurexins and neuroligins | Homo sapiens |
| RAF/MAP kinase cascade | Homo sapiens |
| Ras activation upon Ca2+ influx through NMDA receptor | Homo sapiens |
| Synaptic adhesion-like molecules | Homo sapiens |
| Unblocking of NMDA receptors, glutamate binding and activation | Homo sapiens |
