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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Group 10 secretory phospholipase A2
Summary
- UniProt ID
- O15496
- Gene Symbol
-
- PLA2G10
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- O15496
- PubChem
- O15496
- SwissLipids
- The Human Metabolome Database
- HMDBP00063
- The O-GlcNAc Database
- O15496
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Cleavage on pair of basic residues
- Cytoplasmic vesicle
- Disulfide bond
- Glycoprotein
- Hydrolase
- Lysosome
- Metal-binding
- Phospholipid metabolism
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| positive regulation of prostaglandin secretion |
| low-density lipoprotein particle remodeling |
| intestinal stem cell homeostasis |
| platelet activating factor catabolic process |
| GO Term |
|---|
| acrosomal vesicle |
| extracellular region |
| extracellular space |
| lysosome |
Sequence
MGPLPVCLPIMLLLLLPSLLLLLLLPGPGSGEASRILRVHRRGILELAGTVGCVGPRTPIAYMKYGCFCGLGGHGQPRDAIDWCCHGHDCCYTRAEEAGCSPKTERYSWQCVNQSVLCGPAENKCQELLCKCDQEIANCLAQTEYNLKYLFYPQFLCEPDSPKCD
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 113 | N-linked (GlcNAc...) asparagine |
|
||
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Acyl chain remodelling of PC | Homo sapiens |
| Acyl chain remodelling of PE | Homo sapiens |
| Acyl chain remodelling of PG | Homo sapiens |
| Acyl chain remodelling of PI | Homo sapiens |
| Acyl chain remodelling of PS | Homo sapiens |
| Synthesis of PA | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1325 | bronchus cancer | |
| DOID:13739 | nutmeg liver | |
| DOID:1386 | abetalipoproteinemia | |
| DOID:1387 | hypolipoproteinemia | |
| DOID:1388 | Tangier disease | |
| DOID:1391 | Norum disease | |
| DOID:14268 | sclerosing cholangitis | |
| DOID:14269 | suppurative cholangitis | |
| DOID:14270 | ascending cholangitis | |
| DOID:1520 | colon carcinoma |
