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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Group 10 secretory phospholipase A2
Summary
- UniProt ID
- O15496
- Gene Symbol
-
- PLA2G10
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- O15496
- PubChem
- O15496
- SwissLipids
- The Human Metabolome Database
- HMDBP00063
- The O-GlcNAc Database
- O15496
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Cleavage on pair of basic residues
- Cytoplasmic vesicle
- Disulfide bond
- Glycoprotein
- Hydrolase
- Lysosome
- Metal-binding
- Phospholipid metabolism
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| cholesterol homeostasis |
| negative regulation of DNA-binding transcription factor activity |
| prostaglandin biosynthetic process |
| phosphatidylserine metabolic process |
| GO Term |
|---|
| acrosomal vesicle |
| extracellular region |
| extracellular space |
| lysosome |
Sequence
MGPLPVCLPIMLLLLLPSLLLLLLLPGPGSGEASRILRVHRRGILELAGTVGCVGPRTPIAYMKYGCFCGLGGHGQPRDAIDWCCHGHDCCYTRAEEAGCSPKTERYSWQCVNQSVLCGPAENKCQELLCKCDQEIANCLAQTEYNLKYLFYPQFLCEPDSPKCD
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 113 | N-linked (GlcNAc...) asparagine |
|
||
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Acyl chain remodelling of PC | Homo sapiens |
| Acyl chain remodelling of PE | Homo sapiens |
| Acyl chain remodelling of PG | Homo sapiens |
| Acyl chain remodelling of PI | Homo sapiens |
| Acyl chain remodelling of PS | Homo sapiens |
| Synthesis of PA | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:5672 | large intestine cancer | |
| DOID:5675 | cribriform carcinoma | |
| DOID:614 | lymphopenia | |
| DOID:657 | adenoma | |
| DOID:6726 | fibrillary astrocytoma | |
| DOID:6811 | juvenile pilocytic astrocytoma | |
| DOID:684 | hepatocellular carcinoma | |
| DOID:7005 | gemistocytic astrocytoma | |
| DOID:7007 | childhood cerebral astrocytoma | |
| DOID:7008 | protoplasmic astrocytoma |
