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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
NPC intracellular cholesterol transporter 1
Summary
- UniProt ID
- O35604
- Gene Symbol
-
- Npc1
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003118
- GlyConnect
- GlyGen
- O35604
- PubChem
- O35604
- SwissLipids
- RaftProt
- O35604
Annotation
- Keyword
-
- Cholesterol metabolism
- Disulfide bond
- Endosome
- Glycoprotein
- Lipid transport
- Lysosome
- Reference proteome
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| neurogenesis |
| establishment of localization in cell |
| cholesterol storage |
| sterol transport |
| membrane raft organization |
| intracellular lipid transport |
| intracellular cholesterol transport |
| response to cadmium ion |
| cyclodextrin metabolic process |
| autophagy |
| GO Term |
|---|
| endosome |
| endoplasmic reticulum |
| Golgi apparatus |
| perinuclear region of cytoplasm |
| extracellular region |
| nuclear envelope |
| lysosome |
| plasma membrane |
| membrane |
| vesicle |
| GO Term |
|---|
| lipid transporter activity |
| cholesterol binding |
Sequence
MGAHHPALGLLLLLLCPAQVFSQSCVWYGECGIATGDKRYNCKYSGPPKPLPKDGYDLVQELCPGLFFDNVSLCCDIQQLQTLKSNLQLPLQFLSRCPSCFYNLMTLFCELTCSPHQSQFLNVTATEDYFDPKTQENKTNVKELEYFVGQSFANAMYNACRDVEAPSSNEKALGLLCGRDARACNATNWIEYMFNKDNGQAPFTIIPVFSDLSILGMEPMRNATKGCNESVDEVTGPCSCQDCSIVCGPKPQPPPPPMPWRIWGLDAMYVIMWVTYVAFLFVFFGALLAVWCHRRRYFVSEYTPIDSNIAFSVNSSDKGEASCCDPLGAAFDDCLRRMFTKWGAFCVRNPTCIIFFSLAFITVCSSGLVFVQVTTNPVELWSAPHSQARLEKEYFDKHFGPFFRTEQLIIQAPNTSVHIYEPYPAGADVPFGPPLNKEILHQVLDLQIAIESITASYNNETVTLQDICVAPLSPYNKNCTIMSVLNYFQNSHAVLDSQVGDDFYIYADYHTHFLYCVRAPASLNDTSLLHGPCLGTFGGPVFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTERLQRAWAWEKEFISFVKNYKNPNLTISFTAERSIEDELNRESNSDVFTVIISYVVMFLYISLALGHIQSCSRLLVDSKISLGIAGILIVLSSVACSLGIFSYMGMPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLQEETLDQQLGRILGEVAPTMFLSSFSETSAFFFGALSSMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNHLDILCCVRGADDGQGSHASESYLFRFFKNYFAPLLLKDWLRPIVVAVFVGVLSFSVAVVNKVDIGLDQSLSMPNDSYVIDYFKSLAQYLHSGPPVYFVLEEGYNYSSRKGQNMVCGGMGCDNDSLVQQIFNAAELDTYTRVGFAPSSWIDDYFDWVSPQSSCCRLYNVTHQFCNASVMDPTCVRCRPLTPEGKQRPQGKEFMKFLPMFLSDNPNPKCGKGGHAAYGSAVNIVGDDTYIGATYFMTYHTILKTSADYTDAMKKARLIASNITETMRSKGSDYRVFPYSVFYVFYEQYLTIIDDTIFNLSVSLGSIFLVTLVVLGCELWSAVIMCITIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTMSTKGSRVSRAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFEIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPSVNKAKRHTTYERYRGTERERLLNF
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 524 | N-linked (GlcNAc...) asparagine |
|
||
| 598 |
|
|||
| 868 | N-linked (GlcNAc...) asparagine | |||
| 898 | N-linked (GlcNAc...) asparagine |
|
||
| 916 | N-linked (GlcNAc...) asparagine |
|
||
| 961 | N-linked (GlcNAc...) asparagine | |||
| 968 | N-linked (GlcNAc...) asparagine | |||
| 1063 | N-linked (GlcNAc...) asparagine |
G11314AS
G07246CJ
G26436YP
G86234IN
G70101JE
G80920RR
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| LDL clearance | Mus musculus |
