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MIRAGE
Adenylate cyclase type 6
Summary
- UniProt ID
- O43306
- Gene Symbol
-
- ADCY6
- KIAA0422
- Gene ID
- 112
- Organism
- Homo sapiens (human)
External Links
- PubChem
- O43306
- The Human Metabolome Database
- HMDBP00706
- RaftProt
- O43306
- Re-Glyco
- O43306
Annotation
- Keyword
-
- ATP-binding
- Alternative splicing
- Cell membrane
- Cilium
- Disease variant
- Glycoprotein
- Lyase
- Magnesium
- Manganese
- Metal-binding
- Phosphoprotein
- Reference proteome
- Repeat
- Transmembrane helix
- cAMP biosynthesis
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| cilium |
| membrane |
| stereocilium |
| GO Term |
|---|
| metal ion binding |
| adenylate cyclase activity |
| protein kinase C binding |
| ATP binding |
| protein kinase binding |
Sequence
MSWFSGLLVPKVDERKTAWGERNGQKRSRRRGTRAGGFCTPRYMSCLRDAEPPSPTPAGPPRCPWQDDAFIRRGGPGKGKELGLRAVALGFEDTEVTTTAGGTAEVAPDAVPRSGRSCWRRLVQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLTAVLLAFHAAPARPQPAYVALLACAAALFVGLMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGGALAADPRSPSAGLWCPVFFVYIAYTLLPIRMRAAVLSGLGLSTLHLILAWQLNRGDAFLWKQLGANVLLFLCTNVIGICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTKKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNAYLKEQHIETFLILGASQKRKEEKAMLAKLQRTRANSMEGLMPRWVPDRAFSRTKDSKAFRQMGIDDSSKDNRGTQDALNPEDEVDEFLSRAIDARSIDQLRKDHVRRFLLTFQREDLEKKYSRKVDPRFGAYVACALLVFCFICFIQLLIFPHSTLMLGIYASIFLLLLITVLICAVYSCGSLFPKALQRLSRSIVRSRAHSTAVGIFSVLLVFTSAIANMFTCNHTPIRSCAARMLNLTPADITACHLQQLNYSLGLDAPLCEGTMPTCSFPEYFIGNMLLSLLASSVFLHISSIGKLAMIFVLGLIYLVLLLLGPPATIFDNYDLLLGVHGLASSNETFDGLDCPAAGRVALKYMTPVILLVFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEERFRQLEKIKTIGSTYMAASGLNASTYDQVGRSHITALADYAMRLMEQMKHINEHSFNNFQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKGYQLECRGVVKVKGKGEMTTYFLNGGPSS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 793 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ADORA2B mediated anti-inflammatory cytokines production | Homo sapiens |
| Adenylate cyclase activating pathway | Homo sapiens |
| Adenylate cyclase inhibitory pathway | Homo sapiens |
| Adrenaline,noradrenaline inhibits insulin secretion | Homo sapiens |
| FCGR3A-mediated IL10 synthesis | Homo sapiens |
| G alpha (i) signalling events | Homo sapiens |
| G alpha (s) signalling events | Homo sapiens |
| G alpha (z) signalling events | Homo sapiens |
| GPER1 signaling | Homo sapiens |
| Glucagon signaling in metabolic regulation | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060558 | lethal congenital contracture syndrome |
