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Growth hormone receptor

Summary

UniProt ID

O46600

Gene Symbol

GHR

Organism

Bos taurus (domestic cattle)

External Links

Annotation

Keyword

Cell membrane
Disulfide bond
Endocytosis
Glycoprotein
Phosphoprotein
Receptor
Reference proteome
Secreted
Signal
Transmembrane helix
Ubl conjugation

Gene Ontology (GO)

Displaying **all 5** entries
GO Term
endocytosis
cytokine-mediated signaling pathway
growth hormone receptor signaling pathway
positive regulation of receptor signaling pathway via JAK-STAT
positive regulation of peptidyl-tyrosine phosphorylation

Displaying **all 5** entries
GO Term
growth hormone receptor complex
cytosol
external side of plasma membrane
extracellular region
membrane

Displaying **all 4** entries
GO Term
peptide hormone binding
growth factor binding
cytokine binding
growth hormone receptor activity

Annotation information from UniProt.

Sequence

MDLWQLLLTLAVAGSSDAFSGSEATPAFLVRASQSLQILYPVLETNSSGNPKFTKCRSPELETFSCHWTDGANHSLQSPGSVQMFYIRRDIQEWKECPDYVSAGENSCYFNSSYTSVWTPYCIKLTSNGGIVDHKCFSVEDIVQPDPPVGLNWTLLNISLTEIHADILVKWEPPPNTDVKMGWIILEYELHYKELNETQWKMMDPLMVTSVPMYSLRLDKEYEVRVRTRQRNTEKYGKFSEVLLITFPQMNPSACEEDFQFPWFLIIIFGILGLAVTLYLLIFSKQQRIKMLILPPVPVPKIKGIDPDLLKEGKLEEVNTILAIHDNYKHEFYNDDSWVEFIELDIDDPDEKTEGSDTDRLLSNDHEKSLNIFGAKDDDSGRTSCYEPDILEADFHVSDMCDGTSEVAQPQRLKGEADISCLDQKNQNNSPSNDAAPASQQPSVILVEENKPRPLLIGGTESTHQAVHTQLSNPSSLANIDFYAQVSDITPAGNVVLSPGQKNKTGNPQCDTHPEVVTPCQANFIVDNAYFCEVDAKKYIALAPHVEAESHVEPSFNQEDIYITTESLTTTAGRSGTAEHVPSSEIPVPDYTSIHIVQSPQGLVLNATALPLPDKEFLSSCGYVSTDQLNKIMP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	Source
46	N-linked (GlcNAc...) asparagine	UniProt
73	N-linked (GlcNAc...) asparagine	UniProt
111	N-linked (GlcNAc...) asparagine	UniProt
152	N-linked (GlcNAc...) asparagine	UniProt
157	N-linked (GlcNAc...) asparagine	UniProt
196	N-linked (GlcNAc...) asparagine	UniProt