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Activated CDC42 kinase 1

Summary

UniProt ID

O54967

Gene Symbol

Tnk2
Ack1

Organism

Mus musculus (house mouse)

External Links

GlyGen: O54967
PubChem: O54967
The Human Metabolome Database: HMDBP13422
The O-GlcNAc Database: O54967
O-GlcNAcAtlas: O54967

Annotation

Keyword

ATP-binding
Alternative splicing
Cell junction
Cell membrane
Coated pit
Cytoplasm
Cytoplasmic vesicle
Endocytosis
Endosome
Magnesium
Metal-binding
Methylation
Nucleus
Phosphoprotein
Reference proteome
SH3 domain
Serine/threonine-protein kinase
Tyrosine-protein kinase
Ubl conjugation

Gene Ontology (GO)

Displaying **all 6** entries
GO Term
negative regulation of epidermal growth factor receptor signaling pathway
regulation of keratinocyte differentiation
endocytosis
signal transduction
spermatid development
phosphorylation

Displaying entries **1 - 10** of 13 in total

1

2

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GO Term
dendrite
cytoplasmic vesicle membrane
neuronal cell body
clathrin-coated vesicle
growth cone
cytosol
endosome
clathrin-coated pit
adherens junction
nucleus

Displaying **all 8** entries
GO Term
protein serine kinase activity
WW domain binding
protein serine/threonine/tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
ATP binding
protein serine/threonine kinase activity
protein tyrosine kinase activity
metal ion binding

Annotation information from UniProt.

Sequence

MQPEEGTGWLLELLSEVQLQQYFLRLRDDLNITRLSHFEYVKNEDLEKIGMGRPGQRRLWEAVKRRKAMCKRKSWMSKVFSGKRLEAEFPSQHSQSTFRKPSPTPGSLPGEGTLQSLTCLIGEKDLRLLEKLGDGSFGVVRRGEWDAPAGKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTLPMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMAYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAPESLKTRTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRDFLLEAQPTDMRALQDFEEPDKLHIQMNDVITVIEGRAENYWWRGQNTRTLCVGPFPRNVVTSVAGLSAQDISQPLQNSFIHTGHGDSDPRHCWGFPDRIDELYLGNPMDPPDLLSVELSTSRPTQHLGRVKREPPPRPPQPAIFTQKTTYDPVSEDPDPLSSDFKRLGLRKPALPRGLWLAKPSARVPGTKADRSSGGEVTLIDFGEEPVVPTPRPCAPSLAQLAMDACSLLDKTPPQSPTRALPRPLHPTPVVDWDARPLPPPPAYDDVAQDEDDFEVCSINSTLVGAGLPAGPSQGETNYAFVPEQAQMPPALEDNLFLPPQGGGKPPSSVQTAEIFQALQQECMRQLQVPTGQLTPSPTPGGDDKPQVPPRVPIPPRPTRPRVELSPAPSGEEETSRWPGPASPPRVPPREPLSPQGSRTPSPLVPPGSSPLPHRLSSSPGKTMPTTQSFASDPKYATPQVIQAPGPRAGPCILPIVRDGRKVSSTHYYLLPERPPYLERYQRFLREAQSPEEPAALPVPPLLPPPSTPAPAAPTATVRPMPQAAPDPKANFSTNNSNPGARPPSLRAAARLPQRGCPGDGQEAARPADKVQMLQAMVHGVTTEECQAALQSHSWSVQRAAQYLKVEQLFGLGLRPRVECHKVLEMFDWNLEQAGCHLLGSCGPAHHKR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites