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MIRAGE
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
Summary
- UniProt ID
- O60331
- Gene Symbol
-
- KIAA0589
- PIP5K1C
- Gene ID
- 23396
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- O60331
- PubChem
- O60331
- SwissLipids
- The Human Metabolome Database
- HMDBP03290
- Re-Glyco
- O60331
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Alternative splicing
- Cell adhesion
- Cell junction
- Cell membrane
- Cell projection
- Chemotaxis
- Cytoplasm
- Disease variant
- Endocytosis
- Exocytosis
- Kinase
- Lipid metabolism
- Methylation
- Nucleus
- Phagocytosis
- Phosphoprotein
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| presynapse |
| nucleoplasm |
| cytosol |
| adherens junction |
| focal adhesion |
| endosome membrane |
| ruffle membrane |
| uropod |
| phagocytic cup |
| GO Term |
|---|
| ATP binding |
| 1-phosphatidylinositol-4-phosphate 5-kinase activity |
| phosphatidylinositol kinase activity |
Sequence
MELEVPDEAESAEAGAVPSEAAWAAESGAAAGLAQKKAAPTEVLSMTAQPGPGHGKKLGHRGVDASGETTYKKTTSSTLKGAIQLGIGYTVGHLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNNILPRVVKMHLKFDLKGSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTFSALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQHERERQAQGAQSTSDEKRPVGQKALYSTAMESIQGGAARGEAIESDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDGDTVSVHRPSFYAERFFKFMSNTVFRKNSSLKSSPSKKGRGGALLAVKPLGPTAAFSASQIPSEREEAQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSPSETSEQPRYRRRTQSSGQDGRPQEEPPAEEDLQQITVQVEPACSVEIVVPKEEDAGVEASPAGASAAVEVETASQASDEEGAPASQASDEEDAPATDIYFPTDERSWVYSPLHYSAQAPPASDGESDT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 472 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Clathrin-mediated endocytosis | Homo sapiens |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Homo sapiens |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | Homo sapiens |
| Synthesis of PIPs at the plasma membrane | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060653 | lethal congenital contracture syndrome 3 |
