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Toll-like receptor 2

Summary

UniProt ID

O60603

Gene Symbol

TLR2
TIL4

Organism

Homo sapiens (human)

External Links

GlyConnect

1816

GlyGen

O60603

PubChem

O60603

The Human Metabolome Database

HMDBP12412

Annotation

Keyword

3D-structure
Cytoplasmic vesicle
Disulfide bond
Glycoprotein
Inflammatory response
Innate immunity
Isopeptide bond
Leucine-rich repeat
NAD
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Ubl conjugation

Gene Ontology (GO)

Displaying entries **41 - 50** of 50 in total

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GO Term
toll-like receptor 2 signaling pathway
toll-like receptor TLR6:TLR2 signaling pathway
detection of triacyl bacterial lipopeptide
detection of diacyl bacterial lipopeptide
cellular response to bacterial lipopeptide
cellular response to lipoteichoic acid
cellular response to diacyl bacterial lipopeptide
cellular response to triacyl bacterial lipopeptide
positive regulation of cellular response to macrophage colony-stimulating factor stimulus
positive regulation of matrix metallopeptidase secretion

Displaying entries **1 - 10** of 12 in total

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GO Term
cytoplasm
Golgi apparatus
plasma membrane
secretory granule membrane
cell projection
receptor complex
cell body
phagocytic vesicle membrane
membrane raft
cell surface

Displaying entries **1 - 10** of 12 in total

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GO Term
transmembrane signaling receptor activity
signaling receptor activity
pattern recognition receptor activity
protein-containing complex binding
NAD+ nucleotidase, cyclic ADP-ribose generating
peptidoglycan binding
identical protein binding
lipopolysaccharide binding
amyloid-beta binding
lipopolysaccharide immune receptor activity

Annotation information from UniProt.

Sequence

MPHTLWMVWVLGVIISLSKEESSNQASLSCDRNGICKGSSGSLNSIPSGLTEAVKSLDLSNNRITYISNSDLQRCVNLQALVLTSNGINTIEEDSFSSLGSLEHLDLSYNYLSNLSSSWFKPLSSLTFLNLLGNPYKTLGETSLFSHLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELEIDASDLQSYEPKSLKSIQNVSHLILHMKQHILLLEIFVDVTSSVECLELRDTDLDTFHFSELSTGETNSLIKKFTFRNVKITDESLFQVMKLLNQISGLLELEFDDCTLNGVGNFRASDNDRVIDPGKVETLTIRRLHIPRFYLFYDLSTLYSLTERVKRITVENSKVFLVPCLLSQHLKSLEYLDLSENLMVEEYLKNSACEDAWPSLQTLILRQNHLASLEKTGETLLTLKNLTNIDISKNSFHSMPETCQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNNLNLFSLNLPQLKELYISRNKLMTLPDASLLPMLLVLKISRNAITTFSKEQLDSFHTLKTLEAGGNNFICSCEFLSFTQEQQALAKVLIDWPANYLCDSPSHVRGQQVQDVRLSVSECHRTALVSGMCCALFLLILLTGVLCHRFHGLWYMKMMWAWLQAKRKPRKAPSRNICYDAFVSYSERDAYWVENLMVQELENFNPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKTVFVLSENFVKSEWCKYELDFSHFRLFDENNDAAILILLEPIEKKAIPQRFCKLRKIMNTKTYLEWPMDEAQREGFWVNLRAAIKS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
114	N-linked (GlcNAc...) asparagine	15173186 17889651		UniProt GlyGen
199	N-linked (GlcNAc...) asparagine	15173186 17889651	G08146BT G22310AV G71146HJ G75983OB	UniProt GlyGen GlyConnect
414	N-linked (GlcNAc...) asparagine	17889651	G45395BF G40926MX G83229XP G00912UN G25451PN G27058EU G45495MK G84452RH G70101JE G80920RR G62765YT	UniProt GlyGen GlyConnect
442	N-linked (GlcNAc...) asparagine	15173186 17889651	G83460ZZ G80920RR G62765YT	UniProt GlyGen