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MIRAGE
Keratocan

Summary
UniProt ID
O60938
Gene Symbol
  • KERA
  • SLRR2B
Gene ID
11081
Organism
Homo sapiens (human)
GlyConnect
GlyGen
O60938
The Human Metabolome Database
HMDBP02315
The O-GlcNAc Database
O60938
O-GlcNAcAtlas
O60938
Re-Glyco
O60938
Annotation
Keyword
  • Disease variant
  • Disulfide bond
  • Extracellular matrix
  • Leucine-rich repeat
  • Proteoglycan
  • Reference proteome
  • Repeat
  • Signal
  • Vision
Gene Ontology (GO)
Displaying all 5 entries
GO Term
extracellular region
extracellular space
extracellular matrix
Golgi lumen
lysosomal lumen
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying all 2 entries
GO Term
cornea development in camera-type eye
visual perception
Annotation information from UniProt.
Sequence
MAGTICFIMWVLFITDTVWSRSVRQVYEVHDSDDWTIHDFECPMECFCPPSFPTALYCENRGLKEIPAIPSRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFDVSSILDLQLSHNQLTKVPRISAHLQHLHLDHNKIKSVNVSVICPSPSMLPAERDSFSYGPHLRYLRLDGNEIKPPIPMALMTCFRLLQAVII
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 5 entries
Position Description PubMed ID GlyTouCan ID Source
71
93 N-linked (GlcNAc...) (keratan sulfate) asparagine
167 N-linked (GlcNAc...) (keratan sulfate) asparagine
222 N-linked (GlcNAc...) asparagine
298 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 5 entries
Pathway Name Organism
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Homo sapiens
Defective CHST6 causes MCDC1 Homo sapiens
Defective ST3GAL3 causes MCT12 and EIEE15 Homo sapiens
Keratan sulfate biosynthesis Homo sapiens
Keratan sulfate degradation Homo sapiens
Disease
Displaying all 3 entries
DO ID Disease Name Source
DOID:0060287 cornea plana
DOID:11342 arcus senilis
DOID:2566 corneal dystrophy
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025