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Prostaglandin G/H synthase 2

Summary

UniProt ID

O62698

Gene Symbol

PTGS2
COX2

Organism

Bos taurus (cattle)

External Links

PubChem: O62698

Annotation

Keyword

Acetylation
Dioxygenase
Disulfide bond
Glycoprotein
Heme
Membrane
Microsome
Nucleus
Peroxidase
Prostaglandin biosynthesis
Reference proteome
S-nitrosylation
Signal

Gene Ontology (GO)

Displaying entries **1 - 10** of 11 in total

1

2

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GO Term
positive regulation of protein phosphorylation
response to oxidative stress
cellular response to interleukin-1
positive regulation of embryonic development
regulation of neuroinflammatory response
positive regulation of oocyte maturation
positive regulation of meiotic cell cycle process involved in oocyte maturation
cyclooxygenase pathway
meiotic spindle organization
prostaglandin biosynthetic process

Displaying **all 5** entries
GO Term
neuron projection
endoplasmic reticulum membrane
nuclear inner membrane
nuclear outer membrane
cytoplasm

Displaying **all 5** entries
GO Term
metal ion binding
heme binding
peroxidase activity
prostaglandin-endoperoxide synthase activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

Annotation information from UniProt.

Sequence

MLARALLLCAAVALSGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPNTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDFERGPAFTKGKNHGVDLSHIYGESLERQHKLRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHVPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGLTQFVESFTRQRAGRVAGGRNLPVAVEKVSKASIDQSREMKYQSFNEYRKRFLVKPYESFEELTGEKEMAAELEALYGDIDAMEFYPALLVEKPRPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDTHLTKTVTINASSSHSGLDDINPTVLLKERSTEL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	Source
53	N-linked (GlcNAc...) asparagine	UniProt
130	N-linked (GlcNAc...) asparagine	UniProt
396	N-linked (GlcNAc...) asparagine	UniProt
580	N-linked (GlcNAc...) asparagine	UniProt