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Insulin-like growth factor 1 receptor

Summary

UniProt ID

O73798

Gene Symbol

igf1r

Organism

Xenopus laevis (African clawed frog)

External Links

Annotation

Keyword

ATP-binding
Cell membrane
Cleavage on pair of basic residues
Developmental protein
Disulfide bond
Glycoprotein
Manganese
Metal-binding
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Tyrosine-protein kinase

Gene Ontology (GO)

Displaying **all 7** entries
GO Term
insulin-like growth factor receptor signaling pathway
positive regulation of MAPK cascade
oocyte maturation
cellular response to glucose stimulus
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
protein autophosphorylation
regulation of JNK cascade

Displaying **all 3** entries
GO Term
axon
plasma membrane
insulin receptor complex

Displaying **all 9** entries
GO Term
metal ion binding
insulin receptor substrate binding
insulin-like growth factor receptor activity
structural molecule activity
insulin-like growth factor binding
ATP binding
phosphatidylinositol 3-kinase binding
protein tyrosine kinase activity
insulin receptor activity

Annotation information from UniProt.

Sequence

MKAELVPVCTAWILGLLLCLGPAAAKVCGPNMDIRNDVSELKQLRDCVVIEGYLQILLISNAKAEDFRNLRFPNLTVITDYLLLFRVSGLVSLSNLFPNLTVIRGRVLFYNYALVIFEMTDLKEIGLYNLRNITRGAVRIEKNSELCYVSTVDWSLVLDAVYNNYIVGNKPPKECVDLCPGAREKMQICEKSSINNEFADRCWSDEHCQKVCPSVCGKRACSDNNECCHPECLGSCTAPDNDTACVACHHYFYEGRCVPTCPSNTYKFEGWRCITREVCAKMHIWIHSTIPFIIHKGECVYECPSGYMLNKSQSMTCSPCEGPCPKICEEKMKTIDSVTSAQMLEGCTVLKGNLQLNIRKGQNIAAELENFLGLIETVTGYVKIRHSHALVSLSFLKSLRYILGEEQMPGNYSFYVFDNNNLQQLWDWSKHNLTIKEGKIRFAFNSKLCASEIYRMEEVTGTKGRQAEEDISLSTNGNMASCESHVLNFTSRSKIKNRIKLTWERYRPPDYRDLISFTVYYKEAPFRNVTEYDGQDACGSNSWNMVDVDLPASKESDPGILLQGLKPWTQYAIYVKAITLTMLENRHIHGAKSKIIYMRTDAAVPSIPQDMISASNSSSQLVVKWNPPSLPNGNLSYYIVRWQQQPQDRHLYQYNYCFKDKVPNRKYANGTIDTEGGTEPTKPEGSVGEKGHYCACPKTEAEEKAEKDEAEYRKVFENFLHNSIFVPRPNRRRRDVLAVGNSTVTSYEKNSTTEDFSNFSDSERDDIEYPFYETKVDYKWERTVISNLQPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAAGADDIPGIVNTKEEDDGVIFLGWPEPLRPNGLILMYEIEYKHQGEVHRECVSRQDYRKNGGIKLVRLPPGNYSAQVQAISLYGNGSWTEMVSFCVKLKPDVRNNILQMVVAIPLALSFLLVGIISIVCFVFKKRNSNRLGNGVLYASVNPEYFSAAEMYVPDKWEVPREKITMNRELGQGSFGMVYEGIAKGVVKDEAETKVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPDTESNSGQPTPSLKKMIQMAGEIADGMSYLNANKFVHRDLAARNCMVTEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTNSDVWSFGVVLWEIATLAEQPYQGMSNEQVLRFVMEGGLLEKPDNCPDMLFELMRMCWQFNPKMRPSFLEIISSIKDELDPGFKEVSFFYSEENKPPDTEELDLEAENMESIPLDPSCALQNSEHHAGHKSENGPGVVVLRASFDERQPYAHMNGGRKNERALPLPQSSAC

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **11 - 17** of 17 in total

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Position	Description	Source
634	N-linked (GlcNAc...) asparagine	UniProt
669	N-linked (GlcNAc...) asparagine	UniProt
741	N-linked (GlcNAc...) asparagine	UniProt
750	N-linked (GlcNAc...) asparagine	UniProt
758	N-linked (GlcNAc...) asparagine	UniProt
895	N-linked (GlcNAc...) asparagine	UniProt
908	N-linked (GlcNAc...) asparagine	UniProt