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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
SLIT-ROBO Rho GTPase-activating protein 2
Summary
- UniProt ID
- O75044
- Gene Symbol
-
- SRGAP2
- ARHGAP34
- FNBP2
- KIAA0456
- SRGAP2A
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Cell projection
- Chromosomal rearrangement
- Coiled coil
- Cytoplasm
- Cytoplasmic vesicle
- GTPase activation
- Methylation
- Neurogenesis
- Nucleus
- Phosphoprotein
- Postsynaptic cell membrane
- Reference proteome
- SH3 domain
- Gene Ontology (GO)
| GO Term |
|---|
| filopodium assembly |
| regulation of small GTPase mediated signal transduction |
| excitatory synapse assembly |
| inhibitory synapse assembly |
| GO Term |
|---|
| cytoplasm |
| cytosol |
| nucleus |
| plasma membrane |
| postsynaptic membrane |
| lamellipodium |
| postsynaptic density |
| phagocytic vesicle |
| dendritic spine head |
| GO Term |
|---|
| GTPase activator activity |
| identical protein binding |
| protein homodimerization activity |
| small GTPase binding |
Sequence
MTSPAKFKKDKEIIAEYDTQVKEIRAQLTEQMKCLDQQCELRVQLLQDLQDFFRKKAEIEMDYSRNLEKLAERFLAKTRSTKDQQFKKDQNVLSPVNCWNLLLNQVKRESRDHTTLSDIYLNNIIPRFVQVSEDSGRLFKKSKEVGQQLQDDLMKVLNELYSVMKTYHMYNADSISAQSKLKEAEKQEEKQIGKSVKQEDRQTPRSPDSTANVRIEEKHVRRSSVKKIEKMKEKRQAKYTENKLKAIKARNEYLLALEATNASVFKYYIHDLSDLIDQCCDLGYHASLNRALRTFLSAELNLEQSKHEGLDAIENAVENLDATSDKQRLMEMYNNVFCPPMKFEFQPHMGDMASQLCAQQPVQSELVQRCQQLQSRLSTLKIENEEVKKTMEATLQTIQDIVTVEDFDVSDCFQYSNSMESVKSTVSETFMSKPSIAKRRANQQETEQFYFTKMKEYLEGRNLITKLQAKHDLLQKTLGESQRTDCSLARRSSTVRKQDSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKNAFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERALHIRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSCQAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTSVEDSTQDVTAEHHTSDDECEPIEAIAKFDYVGRTARELSFKKGASLLLYQRASDDWWEGRHNGIDGLIPHQYIVVQDTEDGVVERSSPKSEIEVISEPPEEKVTARAGASCPSGGHVADIYLANINKQRKRPESGSIRKTFRSDSHGLSSSLTDSSSPGVGASCRPSSQPIMSQSLPKEGPDKCSISGHGSLNSISRHSSLKNRLDSPQIRKTATAGRSKSFNNHRPMDPEVIAQDIEATMNSALNELRELERQSSVKHTPDVVLDTLEPLKTSPVVAPTSEPSSPLHTQLLKDPEPAFQRSASTAGDIACAFRPVKSVKMAAPVKPPATRPKPTVFPKTNATSPGVNSSTSPQSTDKSCTV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 424 |
|
|||
| 425 |
|
|||
| 982 |
|
|||
| 983 |
|
|||
| 989 |
|
|
||
| 990 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CDC42 GTPase cycle | Homo sapiens |
| Inactivation of CDC42 and RAC1 | Homo sapiens |
| RAC1 GTPase cycle | Homo sapiens |
| RAC3 GTPase cycle | Homo sapiens |
| RHO GTPases Activate Formins | Homo sapiens |
| RHOF GTPase cycle | Homo sapiens |
| RHOQ GTPase cycle | Homo sapiens |
| RHOU GTPase cycle | Homo sapiens |
