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Low-density lipoprotein receptor-related protein 4

Summary

UniProt ID

O75096

Gene Symbol

LRP4
KIAA0816
LRP10
MEGF7

Organism

Homo sapiens (human)

External Links

GlyGen: O75096
PubChem: O75096
The O-GlcNAc Database: O75096
RaftProt: O75096
O-GlcNAcAtlas: O75096

Annotation

Keyword

3D-structure
Calcium
Cell membrane
Congenital myasthenic syndrome
Developmental protein
Differentiation
Disease variant
Disulfide bond
EGF-like domain
Endocytosis
Glycoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Wnt signaling pathway

Gene Ontology (GO)

Displaying entries **1 - 10** of 25 in total

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GO Term
generation of neurons
synapse organization
negative regulation of ossification
odontogenesis of dentin-containing tooth
dendrite morphogenesis
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of axonogenesis
limb development
postsynaptic membrane assembly
receptor-mediated endocytosis

Displaying **all 10** entries
GO Term
plasma membrane
neuromuscular junction
dendrite
neuronal cell body
receptor complex
synaptic membrane
apical plasma membrane
plasma membrane raft
cell surface
postsynaptic density

Displaying **all 7** entries
GO Term
hormone binding
apolipoprotein binding
protein homodimerization activity
calcium ion binding
coreceptor activity
receptor tyrosine kinase binding
scaffold protein binding

Annotation information from UniProt.

Sequence

MRRQWGALLLGALLCAHGLASSPECACGRSHFTCAVSALGECTCIPAQWQCDGDNDCGDHSDEDGCILPTCSPLDFHCDNGKCIRRSWVCDGDNDCEDDSDEQDCPPRECEEDEFPCQNGYCIRSLWHCDGDNDCGDNSDEQCDMRKCSDKEFRCSDGSCIAEHWYCDGDTDCKDGSDEENCPSAVPAPPCNLEEFQCAYGRCILDIYHCDGDDDCGDWSDESDCSSHQPCRSGEFMCDSGLCINAGWRCDGDADCDDQSDERNCTTSMCTAEQFRCHSGRCVRLSWRCDGEDDCADNSDEENCENTGSPQCALDQFLCWNGRCIGQRKLCNGVNDCGDNSDESPQQNCRPRTGEENCNVNNGGCAQKCQMVRGAVQCTCHTGYRLTEDGHTCQDVNECAEEGYCSQGCTNSEGAFQCWCETGYELRPDRRSCKALGPEPVLLFANRIDIRQVLPHRSEYTLLLNNLENAIALDFHHRRELVFWSDVTLDRILRANLNGSNVEEVVSTGLESPGGLAVDWVHDKLYWTDSGTSRIEVANLDGAHRKVLLWQNLEKPRAIALHPMEGTIYWTDWGNTPRIEASSMDGSGRRIIADTHLFWPNGLTIDYAGRRMYWVDAKHHVIERANLDGSHRKAVISQGLPHPFAITVFEDSLYWTDWHTKSINSANKFTGKNQEIIRNKLHFPMDIHTLHPQRQPAGKNRCGDNNGGCTHLCLPSGQNYTCACPTGFRKISSHACAQSLDKFLLFARRMDIRRISFDTEDLSDDVIPLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDGTGQEVVVDTSLESPAGLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWENLDRPRDIVVEPMGGYMYWTDWGASPKIERAGMDASGRQVIISSNLTWPNGLAIDYGSQRLYWADAGMKTIEFAGLDGSKRKVLIGSQLPHPFGLTLYGERIYWTDWQTKSIQSADRLTGLDRETLQENLENLMDIHVFHRRRPPVSTPCAMENGGCSHLCLRSPNPSGFSCTCPTGINLLSDGKTCSPGMNSFLIFARRIDIRMVSLDIPYFADVVVPINITMKNTIAIGVDPQEGKVYWSDSTLHRISRANLDGSQHEDIITTGLQTTDGLAVDAIGRKVYWTDTGTNRIEVGNLDGSMRKVLVWQNLDSPRAIVLYHEMGFMYWTDWGENAKLERSGMDGSDRAVLINNNLGWPNGLTVDKASSQLLWADAHTERIEAADLNGANRHTLVSPVQHPYGLTLLDSYIYWTDWQTRSIHRADKGTGSNVILVRSNLPGLMDMQAVDRAQPLGFNKCGSRNGGCSHLCLPRPSGFSCACPTGIQLKGDGKTCDPSPETYLLFSSRGSIRRISLDTSDHTDVHVPVPELNNVISLDYDSVDGKVYYTDVFLDVIRRADLNGSNMETVIGRGLKTTDGLAVDWVARNLYWTDTGRNTIEASRLDGSCRKVLINNSLDEPRAIAVFPRKGYLFWTDWGHIAKIERANLDGSERKVLINTDLGWPNGLTLDYDTRRIYWVDAHLDRIESADLNGKLRQVLVSHVSHPFALTQQDRWIYWTDWQTKSIQRVDKYSGRNKETVLANVEGLMDIIVVSPQRQTGTNACGVNNGGCTHLCFARASDFVCACPDEPDSRPCSLVPGLVPPAPRATGMSEKSPVLPNTPPTTLYSSTTRTRTSLEEVEGRCSERDARLGLCARSNDAVPAAPGEGLHISYAIGGLLSILLILVVIAALMLYRHKKSKFTDPGMGNLTYSNPSYRTSTQEVKIEAIPKPAMYNQLCYKKEGGPDHNYTKEKIKIVEGICLLSGDDAEWDDLKQLRSSRGGLLRDHVCMKTDTVSIQASSGSLDDTETEQLLQEEQSECSSVHTAATPERRGSLPDTGWKHERKLSSESQV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 16 in total

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Position	Description	GlyTouCan ID	Source
70		G43417UB	GlyGen
184		G43417UB	GlyGen
264	N-linked (GlcNAc...) asparagine	G80920RR	UniProt GlyGen
498	N-linked (GlcNAc...) asparagine		UniProt GlyGen
604		G49108TO	GlyGen The O-GlcNAc Database
719	N-linked (GlcNAc...) asparagine		UniProt GlyGen
901	N-linked (GlcNAc...) asparagine	G70696MD	UniProt GlyGen
1077	N-linked (GlcNAc...) asparagine		UniProt GlyGen
1415	N-linked (GlcNAc...) asparagine	G80920RR	UniProt GlyGen
1418			GlyGen