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MIRAGE
Cytokine receptor-like factor 1

Summary
UniProt ID
O75462
Gene Symbol
  • CRLF1
  • UNQ288/PRO327
Gene ID
9244
Organism
Homo sapiens (human)
GlycoProtDB
GPDB0011242
GlyConnect
GlyGen
O75462
PubChem
O75462
Re-Glyco
O75462
Annotation
Keyword
  • 3D-structure
  • Direct protein sequencing
  • Disease variant
  • Disulfide bond
  • Glycoprotein
  • Immunoglobulin domain
  • Phosphoprotein
  • Receptor
  • Reference proteome
  • Repeat
  • Secreted
  • Signal
Gene Ontology (GO)
Displaying all 6 entries
GO Term
CRLF-CLCF1 complex
extracellular region
extracellular space
receptor complex
cytosol
external side of plasma membrane
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying all 2 entries
GO Term
cytokine receptor activity
cytokine binding
Annotation information from UniProt.
Sequence
MPAGRRGPAAQSARRPPPLLPLLLLLCVLGAPRAGSGAHTAVISPQDPTLLIGSSLLATCSVHGDPPGATAEGLYWTLNGRRLPPELSRVLNASTLALALANLNGSRQRSGDNLVCHARDGSILAGSCLYVGLPPEKPVNISCWSKNMKDLTCRWTPGAHGETFLHTNYSLKYKLRWYGQDNTCEEYHTVGPHSCHIPKDLALFTPYEIWVEATNRLGSARSDVLTLDILDVVTTDPPPDVHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQIRYRVEDSVDWKVVDDVSNQTSCRLAGLKPGTVYFVQVRCNPFGIYGSKKAGIWSEWSHPTAASTPRSERPGPGGGACEPRGGEPSSGPVRRELKQFLGWLKKHAYCSNLSFRLYDQWRAWMQKSHKTRNQDEGILPSGRRGTARGPAR
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 7 entries
Position Description PubMed ID GlyTouCan ID Source
92 N-linked (GlcNAc...) asparagine
104 N-linked (GlcNAc...) asparagine
140 N-linked (GlcNAc...) asparagine
168 N-linked (GlcNAc...) asparagine
292 N-linked (GlcNAc...) asparagine
324
382 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
IL-6-type cytokine receptor ligand interactions Homo sapiens
Interleukin-27 signaling Homo sapiens
Disease
Displaying 1 entry
DO ID Disease Name Source
DOID:0080329 cold-induced sweating syndrome 1
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025