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Standards Ontologies Notations
Ficolin-3

Summary
UniProt ID
O75636
Gene Symbol
  • FCN3
  • FCNH
  • HAKA1
Organism
Homo sapiens (human)
External Links
GlycoProtDB
GPDB0011246
GlyConnect
GlyGen
O75636
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Calcium
  • Collagen
  • Complement activation lectin pathway
  • Direct protein sequencing
  • Disulfide bond
  • Glycoprotein
  • Hydroxylation
  • Lectin
  • Metal-binding
  • Reference proteome
  • Repeat
  • Secreted
  • Signal
Gene Ontology (GO)
Annotation information from UniProt.
Sequence
MDLLWILPSLWLLLLGGPACLKTQEHPSCPGPRELEASKVVLLPSCPGAPGSPGEKGAPGPQGPPGPPGKMGPKGEPGDPVNLLRCQEGPRNCRELLSQGATLSGWYHLCLPEGRALPVFCDMDTEGGGWLVFQRRQDGSVDFFRSWSSYRAGFGNQESEFWLGNENLHQLTLQGNWELRVELEDFNGNRTFAHYATFRLLGEVDHYQLALGKFSEGTAGDSLSLHSGRPFTTYDADHDSSNSNCAVIVHGAWWYASCYRSNLNGRYAVSEAAAHKYGIDWASGRGVGHPYRRVRMMLR
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 2 entries
Position Description PubMed ID GlyTouCan ID Source
189 N-linked (GlcNAc...) (complex) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 3 entries
Pathway Name Organism
Ficolins bind to repetitive carbohydrate structures on the target cell surface Homo sapiens
Initial triggering of complement Homo sapiens
Lectin pathway of complement activation Homo sapiens
Disease
Displaying entries 1 - 10 of 47 in total
DO ID Disease Name Source
DOID:419 scleroderma
DOID:5844 myocardial infarction
DOID:0050589 inflammatory bowel disease
DOID:0060192 Crohn's colitis
DOID:0060295 complement component 2 deficiency
DOID:0060297 complement component 4a deficiency
DOID:0060298 complement component 4b deficiency
DOID:0060299 complement component 6 deficiency
DOID:0060300 complement component 7 deficiency
DOID:0060301 type I complement component 8 deficiency
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024