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Sortilin-related receptor

Summary

UniProt ID

O88307

Gene Symbol

Sorl1

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003201

GlyConnect

2735

GlyGen

O88307

The O-GlcNAc Database

O88307

O-GlcNAcAtlas

O88307

Annotation

Keyword

Cell membrane
Cleavage on pair of basic residues
Cytoplasmic vesicle
Developmental protein
Disulfide bond
EGF-like domain
Endocytosis
Endoplasmic reticulum
Endosome
Glycoprotein
Golgi apparatus
Phosphoprotein
Receptor
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix
Transport

Gene Ontology (GO)

Displaying entries **1 - 10** of 30 in total

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GO Term
positive regulation of adipose tissue development
adaptive thermogenesis
negative regulation of BMP signaling pathway
protein retention in Golgi apparatus
receptor-mediated endocytosis
diet induced thermogenesis
protein targeting
protein targeting to lysosome
negative regulation of triglyceride catabolic process
insulin receptor recycling

Displaying entries **1 - 10** of 22 in total

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GO Term
Golgi membrane
extracellular space
Golgi apparatus
plasma membrane
membrane
transport vesicle membrane
neuronal cell body
recycling endosome membrane
early endosome membrane
endosome

Displaying **all 6** entries
GO Term
transmembrane signaling receptor activity
neuropeptide binding
aspartic-type endopeptidase inhibitor activity
amyloid-beta binding
low-density lipoprotein particle binding
small GTPase binding

Annotation information from UniProt.

Sequence

MATRSSRRESRLPFLFALVALLPRGALGGGWTQRLHGGPAPLPQDRGFFVVQGDPRDLRLGTHGDAPGASPAARKPLRTRRSAALQPQPIQVYGQVSLNDSHNQMVVHWAGEKSNVIVALARDSLALARPKSSDVYVSYDYGKSFSKISEKLNFGVGNNSEAVISQFYHSPADNKRYIFVDAYAQYLWITFDFCSTIHGFSIPFRAADLLLHSKASNLLLGFDRSHPNKQLWKSDDFGQTWIMIQEHVKSFSWGIDPYDQPNAIYIERHEPFGFSTVLRSTDFFQSRENQEVILEEVRDFQLRDKYMFATKVVHLPGSQQQSSVQLWVSFGRKPMRAAQFVTKHPINEYYIADAAEDQVFVCVSHSNNSTNLYISEAEGLKFSLSLENVLYYSPGGAGSDTLVRYFANEPFADFHRVEGLQGVYIATLINGSMNEENMRSVITFDKGGTWEFLQAPAFTGYGEKINCELSQGCSLHLAQRLSQLLNLQLRRMPILSKESAPGLIIATGSVGKNLASKTNVYISSSAGARWREALPGPHYYTWGDHGGIIMAIAQGMETNELKYSTNEGETWKTFVFSEKPVFVYGLLTEPGEKSTVFTIFGSNKESVHSWLILQVNATDALGVPCTENDYKLWSPSDERGNECLLGHKTVFKRRTPHATCFNGEDFDRPVVVSNCSCTREDYECDFGFKMSEDLSLEVCVPDPEFSGKPYSPPVPCPVGSSYRRTRGYRKISGDTCSGGDVEARLEGELVPCPLAEENEFILYAMRKSIYRYDLASGATEQLPLSGLRAAVALDFDYERNCLYWSDLALDTIQRLCLNGSTGQEVIINSGLETVEALAFEPLSQLLYWVDAGFKKIEVANPDGDFRLTIVNSSVLDRPRALVLVPQEGVMFWTDWGDLKPGIYRSYMDGSAAYRLVSEDVKWPNGISVDSQWIYWTDAYLDCIERITFSGQQRSVILDSLPHPYAIAVFKNEIYWDDWSQLSIFRASKHSRSQVEILASQLTGLMDMKVFYKGKNAGSNACVPQPCSLLCLPKANNSKSCRCPEGVASSVLPSGDLMCDCPQGYQRKNNTCVKEENTCLRNQYRCSNGNCINSIWWCDFDNDCGDMSDERNCPTTVCDADTQFRCQESGTCIPLSYKCDLEDDCGDNSDESHCEMHQCRSDEFNCSSGMCIRSSWVCDGDNDCRDWSDEANCTAIYHTCEASNFQCHNGHCIPQRWACDGDADCQDGSDEDPVSCEKKCNGFHCPNGTCIPSSKHCDGLRDCPDGSDEQHCEPFCTRFMDFVCKNRQQCLFHSMVCDGIVQCRDGSDEDAAFAGCSQDPEFHKECDEFGFQCQNGVCISLIWKCDGMDDCGDYSDEANCENPTEAPNCSRYFQFHCENGHCIPNRWKCDRENDCGDWSDEKDCGDSHVLPSPTPGPSTCLPNYFHCSSGACVMGTWVCDGYRDCADGSDEEACPSLANSTAASTPTQFGQCDRFEFECHQPKKCIPNWKRCDGHQDCQDGQDEANCPTHSTLTCTSREFKCEDGEACIVLSERCDGFLDCSDESDEKACSDELTVYKVQNLQWTADFSGDVTLTWMRPKKMPSASCVYNVYYRVVGESIWKTLETHSNKTSTVLKVLKPDTTYQVKVQVHCLNKVHNTNDFVTLRTPEGLPDAPRNLQLSLNSEEEGVILGHWAPPVHTHGLIREYIVEYSRSGSKMWASQRAASNSTEIKNLLLNALYTVRVAAVTSRGIGNWSDSKSITTIKGKVIQAPNIHIDSYDENSLSFTLTMDGDIKVNGYVVNLFWSFDAHKQEKKTLSFRGGSALSHRVSNLTAHTSYEISAWAKTDLGDSPLAFEHILTRGSSPPAPSLKAKAINQTAVECIWTGPKNVVYGIFYATSFLDLYRNPKSVTTSLHNKTVIVSKDEQYLFLVRVLIPYQGPSSDYVVVKMIPDSRLPPRHLHAVHIGKTSALIKWESPYDSPDQDLFYAIAVKDLIRKTDRSYKVRSRNSTVEYSLSKLEPGGKYHIIVQLGNMSKDSSIKITTVSLSAPDALKIITENDHVLLFWKSLALKEKQFNETRGYEIHMSDSAVNLTAYLGNTTDNFFKVSNLKMGHNYTFTVQARCLFGSQICGEPAVLLYDELSSGADAAVIQAARSTDVAAVVVPILFLILLSLGVGFAILYTKHRRLQSSFSAFANSHYSSRLGSAIFSSGDDLGEDDEDAPMITGFSDDVPMVIA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 31 in total

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Position	Description	GlyTouCan ID	Source
99	N-linked (GlcNAc...) asparagine		UniProt GlyGen
158	N-linked (GlcNAc...) asparagine	G29184RN G48584BU G70101JE G64527OM G82119TF G06110VR	GlycoProtDB UniProt GlyGen GlyConnect
367	N-linked (GlcNAc...) asparagine	G22328UA	UniProt GlyGen
368	N-linked (GlcNAc...) asparagine		UniProt GlyGen
430	N-linked (GlcNAc...) asparagine	G02886BB	UniProt GlyGen
616	N-linked (GlcNAc...) asparagine		UniProt GlyGen
674	N-linked (GlcNAc...) asparagine	G48584BU G80920RR G74430RZ G06110VR	UniProt GlyGen GlyConnect
818	N-linked (GlcNAc...) asparagine		UniProt GlyGen
871	N-linked (GlcNAc...) asparagine	G80920RR G06110VR G66538GV	GlycoProtDB UniProt GlyGen GlyConnect
1035	N-linked (GlcNAc...) asparagine		UniProt GlyGen