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Sortilin-related receptor

Summary

UniProt ID

O88307

Gene Symbol

Sorl1

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003201

GlyConnect

2735

GlyGen

O88307

The O-GlcNAc Database

O88307

O-GlcNAcAtlas

O88307

Annotation

Keyword

Cell membrane
Cleavage on pair of basic residues
Cytoplasmic vesicle
Developmental protein
Disulfide bond
EGF-like domain
Endocytosis
Endoplasmic reticulum
Endosome
Glycoprotein
Golgi apparatus
Phosphoprotein
Receptor
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix
Transport

Gene Ontology (GO)

Displaying entries **21 - 30** of 30 in total

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GO Term
positive regulation of protein exit from endoplasmic reticulum
endosome to plasma membrane protein transport
positive regulation of glial cell-derived neurotrophic factor production
negative regulation of amyloid-beta formation
positive regulation of ER to Golgi vesicle-mediated transport
positive regulation of early endosome to recycling endosome transport
positive regulation of protein localization to early endosome
negative regulation of amyloid precursor protein catabolic process
negative regulation of neurofibrillary tangle assembly
positive regulation of endocytic recycling

Displaying entries **11 - 20** of 22 in total

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GO Term
endoplasmic reticulum
endoplasmic reticulum membrane
Golgi cisterna
nuclear envelope lumen
early endosome
multivesicular body
trans-Golgi network
cell surface
multivesicular body membrane
perinuclear region of cytoplasm

Displaying **all 6** entries
GO Term
transmembrane signaling receptor activity
neuropeptide binding
aspartic-type endopeptidase inhibitor activity
amyloid-beta binding
low-density lipoprotein particle binding
small GTPase binding

Annotation information from UniProt.

Sequence

MATRSSRRESRLPFLFALVALLPRGALGGGWTQRLHGGPAPLPQDRGFFVVQGDPRDLRLGTHGDAPGASPAARKPLRTRRSAALQPQPIQVYGQVSLNDSHNQMVVHWAGEKSNVIVALARDSLALARPKSSDVYVSYDYGKSFSKISEKLNFGVGNNSEAVISQFYHSPADNKRYIFVDAYAQYLWITFDFCSTIHGFSIPFRAADLLLHSKASNLLLGFDRSHPNKQLWKSDDFGQTWIMIQEHVKSFSWGIDPYDQPNAIYIERHEPFGFSTVLRSTDFFQSRENQEVILEEVRDFQLRDKYMFATKVVHLPGSQQQSSVQLWVSFGRKPMRAAQFVTKHPINEYYIADAAEDQVFVCVSHSNNSTNLYISEAEGLKFSLSLENVLYYSPGGAGSDTLVRYFANEPFADFHRVEGLQGVYIATLINGSMNEENMRSVITFDKGGTWEFLQAPAFTGYGEKINCELSQGCSLHLAQRLSQLLNLQLRRMPILSKESAPGLIIATGSVGKNLASKTNVYISSSAGARWREALPGPHYYTWGDHGGIIMAIAQGMETNELKYSTNEGETWKTFVFSEKPVFVYGLLTEPGEKSTVFTIFGSNKESVHSWLILQVNATDALGVPCTENDYKLWSPSDERGNECLLGHKTVFKRRTPHATCFNGEDFDRPVVVSNCSCTREDYECDFGFKMSEDLSLEVCVPDPEFSGKPYSPPVPCPVGSSYRRTRGYRKISGDTCSGGDVEARLEGELVPCPLAEENEFILYAMRKSIYRYDLASGATEQLPLSGLRAAVALDFDYERNCLYWSDLALDTIQRLCLNGSTGQEVIINSGLETVEALAFEPLSQLLYWVDAGFKKIEVANPDGDFRLTIVNSSVLDRPRALVLVPQEGVMFWTDWGDLKPGIYRSYMDGSAAYRLVSEDVKWPNGISVDSQWIYWTDAYLDCIERITFSGQQRSVILDSLPHPYAIAVFKNEIYWDDWSQLSIFRASKHSRSQVEILASQLTGLMDMKVFYKGKNAGSNACVPQPCSLLCLPKANNSKSCRCPEGVASSVLPSGDLMCDCPQGYQRKNNTCVKEENTCLRNQYRCSNGNCINSIWWCDFDNDCGDMSDERNCPTTVCDADTQFRCQESGTCIPLSYKCDLEDDCGDNSDESHCEMHQCRSDEFNCSSGMCIRSSWVCDGDNDCRDWSDEANCTAIYHTCEASNFQCHNGHCIPQRWACDGDADCQDGSDEDPVSCEKKCNGFHCPNGTCIPSSKHCDGLRDCPDGSDEQHCEPFCTRFMDFVCKNRQQCLFHSMVCDGIVQCRDGSDEDAAFAGCSQDPEFHKECDEFGFQCQNGVCISLIWKCDGMDDCGDYSDEANCENPTEAPNCSRYFQFHCENGHCIPNRWKCDRENDCGDWSDEKDCGDSHVLPSPTPGPSTCLPNYFHCSSGACVMGTWVCDGYRDCADGSDEEACPSLANSTAASTPTQFGQCDRFEFECHQPKKCIPNWKRCDGHQDCQDGQDEANCPTHSTLTCTSREFKCEDGEACIVLSERCDGFLDCSDESDEKACSDELTVYKVQNLQWTADFSGDVTLTWMRPKKMPSASCVYNVYYRVVGESIWKTLETHSNKTSTVLKVLKPDTTYQVKVQVHCLNKVHNTNDFVTLRTPEGLPDAPRNLQLSLNSEEEGVILGHWAPPVHTHGLIREYIVEYSRSGSKMWASQRAASNSTEIKNLLLNALYTVRVAAVTSRGIGNWSDSKSITTIKGKVIQAPNIHIDSYDENSLSFTLTMDGDIKVNGYVVNLFWSFDAHKQEKKTLSFRGGSALSHRVSNLTAHTSYEISAWAKTDLGDSPLAFEHILTRGSSPPAPSLKAKAINQTAVECIWTGPKNVVYGIFYATSFLDLYRNPKSVTTSLHNKTVIVSKDEQYLFLVRVLIPYQGPSSDYVVVKMIPDSRLPPRHLHAVHIGKTSALIKWESPYDSPDQDLFYAIAVKDLIRKTDRSYKVRSRNSTVEYSLSKLEPGGKYHIIVQLGNMSKDSSIKITTVSLSAPDALKIITENDHVLLFWKSLALKEKQFNETRGYEIHMSDSAVNLTAYLGNTTDNFFKVSNLKMGHNYTFTVQARCLFGSQICGEPAVLLYDELSSGADAAVIQAARSTDVAAVVVPILFLILLSLGVGFAILYTKHRRLQSSFSAFANSHYSSRLGSAIFSSGDDLGEDDEDAPMITGFSDDVPMVIA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **11 - 20** of 31 in total

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Position	Description	GlyTouCan ID	Source
1068	N-linked (GlcNAc...) asparagine	G70101JE G64527OM G95177YH G94854LT G06110VR G74724QE	GlycoProtDB UniProt GlyGen GlyConnect
1164	N-linked (GlcNAc...) asparagine	G46503DX G74724QE	GlycoProtDB UniProt GlyGen GlyConnect
1191	N-linked (GlcNAc...) asparagine		UniProt GlyGen
1246	N-linked (GlcNAc...) asparagine	G80920RR G74724QE	UniProt GlyGen GlyConnect
1367	N-linked (GlcNAc...) asparagine		UniProt GlyGen
1458	N-linked (GlcNAc...) asparagine	G80920RR G14260UH	UniProt GlyGen GlyConnect
1608	N-linked (GlcNAc...) asparagine	G05724UK G02815KT G06110VR G66538GV	GlycoProtDB UniProt GlyGen GlyConnect
1706	N-linked (GlcNAc...) asparagine	G82347DR	UniProt GlyGen
1733	N-linked (GlcNAc...) asparagine	G80920RR	GlycoProtDB UniProt GlyGen
1810	N-linked (GlcNAc...) asparagine	G47950XN	UniProt GlyGen