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Transforming growth factor beta receptor type 3

Summary

UniProt ID

O88393

Gene Symbol

Tgfbr3

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003206
GlyGen: O88393
PubChem: O88393

Annotation

Keyword

3D-structure
Cell membrane
Disulfide bond
Extracellular matrix
Proteoglycan
Receptor
Reference proteome
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 47 in total

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GO Term
blood vessel development
in utero embryonic development
cell population proliferation
positive regulation of cell population proliferation
negative regulation of gene expression
cell migration
cardiac muscle cell proliferation
positive regulation of cardiac muscle cell proliferation
heart trabecula formation
positive regulation of SMAD protein signal transduction

Displaying **all 7** entries
GO Term
extracellular space
cytoplasm
plasma membrane
membrane
receptor complex
endoplasmic reticulum
cell surface

Displaying entries **1 - 10** of 11 in total

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GO Term
transforming growth factor beta receptor activity
type II transforming growth factor beta receptor binding
transforming growth factor beta receptor binding
glycosaminoglycan binding
fibroblast growth factor binding
heparin binding
SMAD binding
activin binding
transforming growth factor beta binding
transforming growth factor beta receptor activity, type III

Annotation information from UniProt.

Sequence

MAVTSHHMVPVFVLMSACLATAGPEPSTRCELSPISASHPVQALMESFTVLSGCASRGTTGLPREVHILNLRSTDQGLGQPQREVTLHLNPIASVHTHHKPVVFLLNSPQPLVWHVKTERLAAGVPRLFLVSEGSVVQFSSGNFSLTAETEERSFPQENEHLLHWAQKEYGAVTSFTELKIARNIYIKVGEDQVFPPTCNIGKNFLSLNYLAEYLQPKAAEGCVLASQPHEKEVHIIELISPNSNPYSTFQVDIIIDIRPAREDPEVVKNLVLILKCKKSVNWVIKSFDVKGNLKVIAPDSIGFGKESERSMTVTKLVRNDYPSTQENLMKWALDNGYSPVTSYTIAPVANRFHLRLENNEEMRDEEVHTIPPELRILLGPDHLPALDSPPFQGEIPNGGFPFPFPDIPRRGWKEGEDRIPRPKEPIIPRVQLLPDHREPEEVQGGVNIALSVKCDNEKMVVAVDKDSFQTNGYSGMELTLLDPSCKAKMNGTHFVLESPLNGCGTRHRRSAPDGVVYYNSIVVQAPSPGDSSGWPDGYEDLESGDNGFPGDTDEGETAPLSRAGVVVFNCSLRQLRSPSGFQDQLDGNATFNMELYNTDLFLVPSPGVFSVAENEHVYVEVSVTKADQDLGFAIQTCFISPYSNPDRMSDYTIIENICPKDDSVKFYSSKRVHFPIPHAEVDKKRFSFVFKSVFNTSLLFLHCELTLCSRNKGSQKLPKCVTPDDACTSLDATMIWTMMQNKKTFTKPLAVVLQVDYKENVPNMKESSPVPPPPQIFHGLDTLTVMGIAFAAFVIGALLTGALWYIYSHTGETARRQQVPTSPPASENSSAAHSIGSTQSTPCSSSSTA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
143	N-linked (GlcNAc...) asparagine			UniProt GlyGen
491	N-linked (GlcNAc...) asparagine		G41247ZX	UniProt GlyGen
533	O-linked (Xyl...) (glycosaminoglycan) serine	9659379		UniProt GlyGen
544	O-linked (Xyl...) (glycosaminoglycan) serine	9659379		UniProt GlyGen
570	N-linked (GlcNAc...) asparagine		G02815KT	GlycoProtDB UniProt GlyGen
589	N-linked (GlcNAc...) asparagine			UniProt GlyGen
696	N-linked (GlcNAc...) asparagine			UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 9** entries
Pathway Name	Organism
FGFR1b ligand binding and activation	Mus musculus
FGFR1c ligand binding and activation	Mus musculus
Signaling by Activin	Mus musculus
Signaling by BMP	Mus musculus
TGF-beta receptor signaling activates SMADs	Mus musculus
TGFBR3 PTM regulation	Mus musculus
TGFBR3 regulates FGF2 signaling	Mus musculus
TGFBR3 regulates TGF-beta signaling	Mus musculus
TGFBR3 regulates activin signaling	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements